Protein Alignment HDAC6 and HDAC11

DIOPT Version :9

• Sequence 1: NP_001259569.1
• Gene: HDAC6 / 32461
• FlyBaseID: FBgn0026428
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_001247296.1
• Gene: HDAC11 / 326120
• FlyBaseID: FBgn0051119
• Length: 343
• Species: Drosophila melanogaster
• Alignment Length: 306
• Identity: 80/306 - (26%)
• Similarity: 132/306 - (43%)
• Gaps: 49/306 - (16%)

  Fly   139 CRELNLTERCLELPSRSATKDEILRLHTEEHFERLK---ETSGIRDDERMEELSSRY-DSIYIHP 199
            |.:|.|.:.....|: ..|||::.|:||.|:.:.|:   ..:.|.:...|..:.:|| ...|:.|
  Fly    66 CAQLQLDDGSFYEPT-ELTKDQLRRIHTREYLKSLRWSMNVACIAEVPLMAFVPNRYIQRSYLRP 129

  Fly   200 STFELSLLASGSTIELVDHLVAGK--AQNGMAIIRPPG-HHAMKAEYNGYCFFNNVALATQHALD 261
            ..|:    |:||       ::|||  ...|.||....| ||.......|:|.:.:::|......:
  Fly   130 MRFQ----AAGS-------ILAGKLALDYGWAINLGGGFHHCCSYRGGGFCPYADISLLIVRLFE 183

  Fly   262 VH--KLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGY 324
            ..  :::||:|:|.|.|.|.|.:|.|.|...|..|.::   :...:|..|.         |....
  Fly   184 QEPFRVRRIMIVDLDAHQGNGHERDFNNVAAVYIFDMY---NAFVYPRDHV---------AKESI 236

  Fly   325 NFNVPL-NATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACY---P 385
            ...|.| |.|  .:|.||...::.|:....||:|::::.:||.|...|.|.|.:.::....   .
  Fly   237 RCAVELRNYT--EDGFYLRQLKRCLMQSLAEFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERD 299

  Fly   386 HLLNPLLRLADARVAVVLEGGY-------CLDSLAEGAALTLRSLL 424
            .|:....|.....|.::|.|||       ..||:..   |.|:.||
  Fly   300 RLVFSTFRALGIPVVMLLSGGYLKASAGVITDSIVN---LRLQGLL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC6	NP_001259569.1	HDAC10_HDAC6-dom1	119..457	CDD:212526	80/306 (26%)
		HDAC6-dom2	538..895	CDD:212527
		zf-UBP	1007..1069	CDD:280334
HDAC11	NP_001247296.1	HDAC_classIV	51..336	CDD:212519	76/298 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458016
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48252
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840