DRSC/TRiP Functional Genomics Resources

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Protein Alignment HDAC6 and Usp49

DIOPT Version :9

Sequence 1:NP_001259569.1 Gene:HDAC6 / 32461 FlyBaseID:FBgn0026428 Length:1179 Species:Drosophila melanogaster
Sequence 2:NP_001129942.1 Gene:Usp49 / 316211 RGDID:1310513 Length:685 Species:Rattus norvegicus


Alignment Length:85 Identity:37/85 - (43%)
Similarity:46/85 - (54%) Gaps:3/85 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   986 CPHLRLLRPEEAPRSLDSGAECSV-CGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMS 1049
            |.|:..||..:....|:....|.: |.:|...|.||.|.|||||||:..|..:|..|..|||||.
  Rat     4 CKHVGRLRLAQDHSILNPQKWCCLECATTESAWACLKCSHVACGRYIEDHALKHFEETGHPLAME 68

  Fly  1050 TADLSVWCYACSAYV--DHP 1067
            ..||.|:||.|..||  |:|
  Rat    69 VRDLYVFCYLCKDYVLNDNP 88

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HDAC6NP_001259569.1 HDAC10_HDAC6-dom1 119..457 CDD:212526
HDAC6-dom2 538..895 CDD:212527
zf-UBP 1007..1069 CDD:280334 32/64 (50%)
Usp49NP_001129942.1 zf-UBP 26..87 CDD:396634 29/60 (48%)
UCH 250..651 CDD:395355
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1867
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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