Protein Alignment HDAC6 and Usp3

DIOPT Version :9

• Sequence 1: NP_001259569.1
• Gene: HDAC6 / 32461
• FlyBaseID: FBgn0026428
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: XP_006511173.1
• Gene: Usp3 / 235441
• MGIID: 2152450
• Length: 606
• Species: Mus musculus
• Alignment Length: 221
• Identity: 57/221 - (25%)
• Similarity: 73/221 - (33%)
• Gaps: 73/221 - (33%)

  Fly   861 GATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNI 925
            |...|..|.....||.....|.||..:|.....|.|:|  .|:.|
Mouse    24 GGVGLAVPRGPDRQSAALRAQLCLDCRRASPFGLRFLG--FPQAP-------------------- 66

  Fly   926 SNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTCPHLR 990
                    |...|.:|...|......|...|:||      .||:                   ||
Mouse    67 --------ASPAAPERTALGAAHLGVSLQPVRVK------FENR-------------------LR 98

  Fly   991 LLR-PEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQH---------------- 1038
            ..: ||:|..|...|| ..||.|....||||:|..|.||||||.|.::|
Mouse    99 APKAPEKAANSCFGGA-ARVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEK 162

  Fly  1039 SVEEQHPLAMSTADLSVWCYACSAYV 1064
            ..:.||.:.|..:..|.:||.|..:|
Mouse   163 QEKAQHTVCMDCSSYSTYCYRCDDFV 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC6	NP_001259569.1	HDAC10_HDAC6-dom1	119..457	CDD:212526
		HDAC6-dom2	538..895	CDD:212527	9/33 (27%)
		zf-UBP	1007..1069	CDD:280334	25/74 (34%)
Usp3	XP_006511173.1	zf-UBP	117..191	CDD:366940	25/72 (35%)
		UCH	245..594	CDD:366104

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810