Protein Alignment HDAC6 and Hdac3

DIOPT Version :9

• Sequence 1: NP_001259569.1
• Gene: HDAC6 / 32461
• FlyBaseID: FBgn0026428
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_034541.2
• Gene: Hdac3 / 15183
• MGIID: 1343091
• Length: 428
• Species: Mus musculus
• Alignment Length: 333
• Identity: 86/333 - (25%)
• Similarity: 157/333 - (47%)
• Gaps: 29/333 - (8%)

  Fly   534 VCYAYDAQMLLHCNLN-DTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAH 597
            |.|.||..:   .|.: ..|||.:|.|:...|.:...|||.|:|....|..|:..::|..|:..:
Mouse     5 VAYFYDPDV---GNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDY 66

  Fly   598 VNTVRRLLGREPKELH------DAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGIC 656
            ::.::|:   .|..:.      :|..:.:...:.|..|:..:...|..||....:     .:.||
Mouse    67 IDFLQRV---SPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQL-----NNKIC 123

  Fly   657 NVR---PPG-HHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPK 717
            ::.   ..| |||::....|||..|::.|.....::..  .|||.:|.|:|||:|.|..|....:
Mouse   124 DIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYH--PRVLYIDIDIHHGDGVQEAFYLTDR 186

  Fly   718 VLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEF 782
            |:.:|.|:|  |::|..| .|:...||..:||.:.:|:|. :.|:.|..|...||.:|..:...:
Mouse   187 VMTVSFHKY--GNYFFPG-TGDMYEVGAESGRYYCLNVPL-RDGIDDQSYKHLFQPVISQVVDFY 247

  Fly   783 NPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCT 847
            .|..:::..|.|:...|.||...::..|:|....::.:. :..::|...|||.|.:::...|..|
Mouse   248 QPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSF-NIPLLVLGGGGYTVRNVARCWTYET 311

  Fly   848 KTLLGDPV 855
            ..|:.:.:
Mouse   312 SLLVEEAI 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC6	NP_001259569.1	HDAC10_HDAC6-dom1	119..457	CDD:212526
		HDAC6-dom2	538..895	CDD:212527	84/329 (26%)
		zf-UBP	1007..1069	CDD:280334
Hdac3	NP_034541.2	HDAC3	3..383	CDD:212529	86/333 (26%)
		Histone deacetylase	3..316		86/328 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..424

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810