Sequence 1: | NP_001259569.1 | Gene: | HDAC6 / 32461 | FlyBaseID: | FBgn0026428 | Length: | 1179 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | XP_016879477.1 | Gene: | HDAC5 / 10014 | HGNCID: | 14068 | Length: | 1161 | Species: | Homo sapiens |
Alignment Length: | 1071 | Identity: | 286/1071 - (26%) |
---|---|---|---|
Similarity: | 427/1071 - (39%) | Gaps: | 287/1071 - (26%) |
- Green bases have known domain annotations that are detailed below.
Fly 66 LEAKRRARNNMLKNQGCGSQESV---TDI---FQNAVNSKSLVRKPTALIYDESMSQHCCLWDKE 124
Fly 125 H-------------------YECPERFTRVLERCRELNLTERCLELPSRSATKDEI-LRLHTEEH 169
Fly 170 FERLKETSGIRD---DERMEELSSRYDSIYIHPSTFE---LSLLASGSTIELVDHLVAGKAQNGM 228
Fly 229 AIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVY 293
Fly 294 FSIH-------RFEHGSFWPHL---HESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAI--FQQ 346
Fly 347 LLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADAR-----VAVVLEGG 406
Fly 407 YCLDSLAEGAALTLRSL------------LGDPCPP----------------------------- 430
Fly 431 --LVETVPLPR-------------AELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDL 480
Fly 481 HTVLRHWIGGPPPMDRYPTRD----TAIPLPPE---------KLTSNAARLQVL----------- 521
Fly 522 -------RAETKLSVPS-------------FKVCYAYDAQMLLH-CNLNDTG-HPEQPSRIQHIH 564
Fly 565 KMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTV------------RRLLGREPKELH---- 613
Fly 614 ------DAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHG 672
Fly 673 FCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPD 737
Fly 738 GNFDVVGKGAGRGFNVNIPWN---KKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIG- 798
Fly 799 -DPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGA 862
Fly 863 TALQKPPTVAFQSCVESLQQCLQVQRNHWRSLE----FVGRRLPRDPVVGENNNEDFLTASLRHL 923
Fly 924 NISNDDATAAAGGLAGDRPDCGDERPSGSKP 954 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
HDAC6 | NP_001259569.1 | HDAC10_HDAC6-dom1 | 119..457 | CDD:212526 | 85/436 (19%) |
HDAC6-dom2 | 538..895 | CDD:212527 | 149/385 (39%) | ||
zf-UBP | 1007..1069 | CDD:280334 | |||
HDAC5 | XP_016879477.1 | None | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D1484694at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100220 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2991 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
6 | 5.750 |