Protein Alignment dah and dyb-1

DIOPT Version :9

• Sequence 1: NP_511162.1
• Gene: dah / 32459
• FlyBaseID: FBgn0015926
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_490860.1
• Gene: dyb-1 / 171715
• WormBaseID: WBGene00001115
• Length: 590
• Species: Caenorhabditis elegans
• Alignment Length: 654
• Identity: 125/654 - (19%)
• Similarity: 212/654 - (32%)
• Gaps: 223/654 - (34%)

  Fly    29 SQGGQGQKQQ------------------VDKELSTIMDDLQ-RDYGNYKYTVYRCASKFVALQKI 74
            |.||.|.::.                  |..|:..::|::: :|:.:.::..||.|.|...:|:
 Worm     4 SNGGGGPREPSSAPSPDHHRAMHSVPPIVASEMQQLIDEMRLQDFDSIRFATYRAACKLRFIQQ- 67

  Fly    75 FHTGKIPYKLVLAILDRHNL-----SGGL--------------ELMVPPFQLTSLLHDVYFACEK 120
                    |..:.::|..|:     ..||              ||:     ||::.|::......
 Worm    68 --------KTKVHLVDIWNMIEAFRENGLNALPLHTVIKTSRAELL-----LTTVFHNLNKRLVA 119

  Fly   121 LGHFNQDANYKLDRATGLLANFFWNVYDPQRRHSISLLEIRITFILLCKLYSSDHLVGDIFGLLA 185
            ..|.:.|.:..|     ||| |....||.|....:::..|::....||.....|.| ..||..:|
 Worm   120 SQHVDTDVSISL-----LLA-FLLGAYDKQNTGRLTVFSIKVALATLCAGKLVDKL-RYIFSQIA 177

  Fly   186 DPKSQIISRYAFEQLLATLSKLLSYLGEAKAYGVHNLPLAMEQCFAR-----------------C 233
            | .:.::....|...|..:..|.:.:.||..:|...  .|:.|||.:                 |
 Worm   178 D-SNGLMDHIKFTDFLQQILSLTTAVFEAPTFGFSE--NAVNQCFHKDEKVSLNVFLDTFLSDPC 239

  Fly   234 PHGVGGLTEPQFHKLWTGAGVQTRFLIYGNLLALVKRIEDTEHLIHSNSCAGCRKEHIVGIRFRC 298
            |..:          :|               |.|:.|:....::.|...|..|:.....|.|::|
 Worm   240 PPCI----------MW---------------LPLLHRMASVSNVYHPVVCDACQVRSFTGFRYKC 279

  Fly   299 QVCRDISLCLPCFAVGFAGGRHEPGHRMCEVFVEDQP--PLRWTRHLARLCGWLVMPRKTQEEER 361
            |.|.:..||..||..|.....|...|.|.|......|  .|..:.|.:..|   :....|..:..
 Worm   280 QRCANYQLCQSCFWRGRTSQNHSNEHEMKEYSSYKSPTKQLVHSIHKSLQC---IPATSTVGDAN 341

  Fly   362 RGFCNAQESGPALGQSA----------ATP---------------------IPAET--------- 386
            ....||:..||...:.|          |||                     :|.:.
 Worm   342 IDIFNAKIGGPVSSKPARPLNLNNIVPATPTTIRRQHAATSSADWPTSPVLLPGQASHGGVIDDE 406

  Fly   387 ----------------------RSVRSQCQEKDRTVVLQQQQQE---LCSLTGLASEASS--RLQ 424
                                  ||:.|.....:||::.|.:::.   :..:..|.|:.:|  .|.
 Worm   407 HKLIARYAAKLSGRADYPLSNGRSMNSSMVGDERTLIAQLEEENSMMVREMARLESQTTSDDGLA 471

  Fly   425 SIIDRLL-LQNAKLETQLQTVATASSSEISQFLSAHQCFLLQIIEDMRQLSHASAVTSPPPAPAA 488
            .:.||.: |:....|.|.:.                       .|.|.||.|..|..:..|.|:.
 Worm   472 GLRDRKMELEEKMFEMQQRR-----------------------RELMMQLEHLMAQLNTGPQPSG 513

  Fly   489 QVAPSAAPL------------------VSSTFLSSSTPQRQMLFDMY---APVGANLTHSINGAD 532
            .|  |:|.|                  |::.|.:.|.|...:..|:.   ..:..|::..:...|
 Worm   514 GV--SSASLSQLPFTASDQQLTGVNSTVANAFRAGSLPATSLQGDLLHAADQITTNMSDLVRQLD 576

  Fly   533 LNRS 536
            |.:|
 Worm   577 LAQS 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dah	NP_511162.1	EF-hand_2	44..168	CDD:286194	28/143 (20%)
		ZZ_dah	281..329	CDD:239085	15/47 (32%)
dyb-1	NP_490860.1	EF-hand_2	38..161	CDD:286194	28/142 (20%)
		EF-hand_3	165..253	CDD:286195	22/116 (19%)
		ZZ_dystrophin	262..310	CDD:239074	15/47 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910