Protein Alignment dah and dah

DIOPT Version :10

• Sequence 1: NP_511162.1
• Gene: dah / 32459
• FlyBaseID: FBgn0015926
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_061499936.1
• Gene: dah / 1270491
• VectorBaseID: AGAMI1_003383
• Length: 661
• Species: Anopheles gambiae
• Alignment Length: 669
• Identity: 217/669 - (32%)
• Similarity: 319/669 - (47%)
• Gaps: 104/669 - (15%)

  Fly    34 GQKQQVDKELSTIMDDLQRDYGNYKYTVYRCASKFVALQKIFHTGKIPYKLVLAILDRHNLSGGL 98
            |:.:|.:..|..|:..:...|...:|:.||||.|..||||..||..||:::|.:||:||.|:
Mosquito    21 GKTEQDNPNLLFILLTINEKYAGARYSTYRCAGKLHALQKALHTSYIPFEMVHSILNRHQLN--- 82

  Fly    99 ELM-----VPPFQLTSLLHDVYFACEKLGHFNQ-DANYKLDRATGLLANFFWNVYDPQRRHSISL 157
             |:     :.|.||.|::||||||..::|:|:: .|...||.|:.|||.|.|.|:||:|...:|:
Mosquito    83 -LIDSAPSIKPGQLASVVHDVYFAAARMGYFDELPARPNLDAASALLAGFLWAVFDPKRTTPVSV 146

  Fly   158 LEIRITFILLCKLYSSDHLVGDIFGLLADPKSQIISRYAFEQLLATLSKLLSYLGEAKAYGVHNL 222
            ||:|..|:|||...:...||.:.|.|.:| .:..:||:.||.:|..|||:|::|||..    |..
Mosquito   147 LELRQAFLLLCDHATHGQLVWEHFRLTSD-HNLCVSRHRFEAMLTVLSKVLTFLGEPD----HLR 206

  Fly   223 PLAMEQ----CFARCPHGVGGLTEPQFHKLWTGAGVQTRFLIYGNLLALVKRIEDTEHLIHSNSC 283
            |..::|    |||..| |:.||||.||..||.   :.:.|..|.|::.|.||:.||||:.|...|
Mosquito   207 PSMVQQITGECFANYP-GLVGLTEYQFCCLWK---LSSLFSYYANVVTLCKRLHDTEHITHGMPC 267

  Fly   284 AGCRKEHIVGIRFRCQVCRDISLCLPCFAVGFAGGRHEPGHRMCEVFV-EDQPPLRWTRHLARLC 347
            .|||.. |.|:||:||.||.:||||.||..|::..||...|:|.|:.. |.:...|.|....::.
Mosquito   268 YGCRAP-IRGLRFKCQRCRHVSLCLDCFTAGYSSKRHSMAHKMYEISAGEGETGSRCTAWADKVW 331

  Fly   348 GWLVMPRKTQEEERRGFCNAQESGPALGQSAATP-IPAETRSVRSQCQEKDRTVVLQQQQQELCS 411
            .||   |.|......|......:..|.|.:...| .|:...::.::..: .:.|.|.|.::.|..
Mosquito   332 RWL---RVTATGGASGASTGSRAAVAGGGNDGLPSAPSTYENLEAKLID-TKAVDLGQSEEALAG 392

  Fly   412 LTGLASE---ASSRLQSIIDRLLLQNAKL----------ETQLQTVATASSSEISQFLSAHQC-- 461
            ......|   .:.|.:|||...|.:|..|          .||.:.|....::.:......|:.
Mosquito   393 EPDAGGERRGTAQRRESIISSTLKRNMSLFSSVEYGAFNNTQQKNVLARLAATLETLEERHEATR 457

  Fly   462 ------------------------FLLQIIEDMRQLSHASAVTSPPPAPAAQVAPSAAPLVSSTF 502
                                    ::.|:.|.:.||....       |...|..|..
Mosquito   458 TRLAKRGEEGGSPTADELRALFEQYVAQVAEGLAQLKDVG-------AQLGQGLPQC-------- 507

  Fly   503 LSSSTPQRQMLFDMYAPVGANLTHSI-NGADLNRSYLEANKSDYSLNDISLWFDQRRSSVQPGQG 566
              ||||.||.     |.:.||.:..: ....:.||.: ..|::.|:.|||.||.......|.|:.
Mosquito   508 --SSTPYRQA-----ASLTANCSSEVEREKSMGRSRI-MEKTELSVRDISTWFHIELDRAQAGET 564

  Fly   567 PGSLPAPLPLPMP-----LGALLEQQPANGGDGRDTEMVNFKLLLHKVKEIVEDSYSDNAELSAA 626
            ....|.....|:|     |...:::..      .||:|.||:.||.||:|||:||||||.||:.:
Mosquito   565 DAKEPLSGERPLPPKRDELSCRIDRLK------MDTQMANFRDLLLKVREIVDDSYSDNTELARS 623

  Fly   627 TQNLENVLDSIIKSEEQQR 645
            ||.:|..||.||..|||:|
Mosquito   624 TQQIEKALDRIIAEEEQKR 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dah	NP_511162.1	EFh_DAH	81..250	CDD:320003	73/178 (41%)
		EF-hand-like motif	81..120	CDD:320003	18/43 (42%)
		EF-hand-like motif	132..166	CDD:320003	17/33 (52%)
		EF-hand-like motif	173..210	CDD:320003	14/36 (39%)
		EF-hand-like motif	223..250	CDD:320003	14/30 (47%)
		ZZ_dah	281..329	CDD:239085	23/47 (49%)
dah	XP_061499936.1	None