Protein Alignment Top1 and timm22

DIOPT Version :9

• Sequence 1: NP_001014742.1
• Gene: Top1 / 32458
• FlyBaseID: FBgn0004924
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_001011397.1
• Gene: timm22 / 496870
• XenbaseID: XB-GENE-5754351
• Length: 186
• Species: Xenopus tropicalis
• Alignment Length: 93
• Identity: 23/93 - (24%)
• Similarity: 34/93 - (36%)
• Gaps: 36/93 - (38%)

  Fly   545 SKEEKLIKKNENEALMKEFGF-----CMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQA 604
            |:|:|::     |.:|:..||     |        :|.|.|  .|.|              .:..
 Frog    48 SEEQKMM-----ERVMESCGFKAALAC--------VGGFVL--GGAF--------------GVFT 83

  Fly   605 SDVSINCGKDSKVPSPPPGSRWKEVRHD 632
            :.:..|.|.|.|.|...|.:  |||..|
 Frog    84 AGIDTNVGFDPKDPYRTPTA--KEVLKD 109

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Top1	NP_001014742.1	Topoisomer_IB_N_htopoI_like	441..655	CDD:239570	23/93 (25%)
		TOPEUc	585..946	CDD:214661	11/48 (23%)
		Topoisom_I	657..859	CDD:279380
		Topo_C_assoc	905..972	CDD:291068
timm22	NP_001011397.1	Tim17	60..182	CDD:280604	18/76 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	331	1.000	Domainoid score	I1157
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	822	1.000	Inparanoid score	I459
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001157
OrthoInspector	1	1.000	-	-		otm49460
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X783
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.050