Protein Alignment gce and ARNT2

DIOPT Version :9

• Sequence 1: NP_001188593.1
• Gene: gce / 32457
• FlyBaseID: FBgn0261703
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: NP_055677.3
• Gene: ARNT2 / 9915
• HGNCID: 16876
• Length: 717
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 122/591 - (20%)
• Similarity: 201/591 - (34%)
• Gaps: 177/591 - (29%)

  Fly   161 SPAHGNPPGFYP----NMWYPNAPYGSAGAAGSAGGAVSGGRYMGYGPGGVPGGTNSG------P 215
            :||..|||....    ::..|.||..:.|....||...:.|           |...||      .
Human     3 TPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARG-----------GKRRSGMDFDDED 56

  Fly   216 GAGPGAMQAAYPGHSAHMHALHHQYPQPHPHAHHPQHPHHSPHPHHPHPHETMMEMFQLSNSGRE 280
            |.||                                                       |...||
Human    57 GEGP-------------------------------------------------------SKFSRE 66

  Fly   281 ARNRAEKNRRDKLNGSIQELSTMVPHVAESPRRVDKTAVLRFAAHALRLKHAFGNS--------- 336
            ..:..|:.||:|:...|.|||.|||..:...|:.||..:||.|...::.....||.
Human    67 NHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPS 131

  Fly   337 -LMQQRPQITDTLMDMLDSFFLTLTCH-GHILLISASIEQHLGHCQSDLYGQSIMQITHPEDQNM 399
             |.:|  ::...:::..|.|...:... |.::.:|.|:...|...||:.:|.::.:..||:|...
Human   132 FLTEQ--ELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEK 194

  Fly   400 LKQQLIPTE---LENLFDAH-GDSDAEGEPRQRSKAEEDAIDRKLREDRRSF--RVRLARA---- 454
            |::||..:|   ...:.|.. |....||   |:|..      |.....||||  |:|...|
Human   195 LREQLCTSENSMTGRILDLKTGTVKKEG---QQSSM------RMCMGSRRSFICRMRCGNAPLDH 250

  Fly   455 -----------------GPRSEPTA-YEVVKIDGCFRRSDEAPRGVRSNHFSSNLQLIRRTRGRD 501
                             ||..|..| |.||...|..:.  ..|.|:
Human   251 LPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKA--WPPAGM------------------- 294

  Fly   502 DVIPLHTISGND----------IILTGCARIIRPPKIASRLIDANTL----EYKTRHLIDGRIID 552
                  ||...|          ::..|..::...|.    .:|.|.:    |:.:||..||.|..
Human   295 ------TIPEEDADVGQGSKYCLVAIGRLQVTSSPV----CMDMNGMSVPTEFLSRHNSDGIITF 349

  Fly   553 CDQRIGIVAGYMTDEVRNLSPFTFMHNDDVRWVIVALRQMYDCNSSYGESTYRLFTRNGNIIYLQ 617
            .|.|...|.||...::.......|.|.:|...:..:.:|:...........||..|:|...:.::
Human   350 VDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIR 414

  Fly   618 SKGYLEIDKETNKVHSFVCVNTLLGEEEGKRRVQEMKKK--FSVIINTQIPQSTIDVPASEHPA- 679
            :..:...:..::::...:|.||.:.:.:.::...|:.::  .|....:|:|  ..::||..|.|
Human   415 TSSFTFQNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVP--VPNLPAGVHEAG 477

  Fly   680 -LLEKA 684
             .:|||
Human   478 KSVEKA 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gce	NP_001188593.1	HLH	279..325	CDD:238036	19/45 (42%)
		PAS	352..>405	CDD:238075	14/53 (26%)
		PAS_11	539..646	CDD:291273	22/106 (21%)
ARNT2	NP_055677.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/16 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..74		13/104 (13%)
		bHLH-PAS_ARNT	62..124	CDD:381517	21/61 (34%)
		PAS	137..243	CDD:395786	28/114 (25%)
		PAS_11	336..436	CDD:405306	20/99 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	548..717

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3561
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740