Protein Alignment gce and bmal2

DIOPT Version :10

• Sequence 1: NP_511160.2
• Gene: gce / 32457
• FlyBaseID: FBgn0261703
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: NP_001096298.1
• Gene: bmal2 / 100124875
• XenbaseID: XB-GENE-6454872
• Length: 594
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 132/586 - (22%)
• Similarity: 207/586 - (35%)
• Gaps: 137/586 - (23%)

  Fly   278 GREARNRAEKNRRDKLNGSIQELSTMVPHVAESPRRVDKTAVLRFAAHALRLKHAFGNSLMQQRP 342
            ||||....||.||:|:|..|:.||.|:|.....|.:.||..|||.|...|:.......|...:.|
 Frog    73 GREAHRETEKRRREKMNNLIENLSAMIPQSGPLPSKPDKLTVLRMAVQHLKSLKGSNPSFADESP 137

  Fly   343 --------QITDTLMDMLDSFFLTLTC-HGHILLISASIEQHLGHCQSDLYGQSIMQITHPEDQN 398
                    ::...::...|.|...:.| .|.||.:|.|:.:.|.:.|.||.|:|:....||:|..
 Frog   138 KPSFLKHEEMKQLILRAADGFLFVIGCDRGEILFVSESVTKTLKYNQGDLMGKSLFDFLHPKDVA 202

  Fly   399 MLKQQLIPTEL---ENLFDA---------------HGDSDAEGEPRQRS-----KAEEDAIDRKL 440
            .:|:||..:::   |.|.||               |..|......|.:|     |.|:|.:....
 Frog   203 KVKEQLSSSDIAPREKLIDAKTGLQVHTHFQASRLHWGSRRSFFCRMKSGRANHKEEKDFLRNSK 267

  Fly   441 REDRRSFRVRLARAGPRSEPTAYEVVKIDGCFRRSDEAPRGVRSNHFSSNLQLIRRTRGRDDVIP 505
            |:|.|.:.........||.|.:.|....|      .|||
 Frog   268 RKDHRRYCTIHCTGYLRSCPPSEEECDTD------REAP-------------------------- 300

  Fly   506 LHTISGNDIILTGCARI---IRPPKIASRLIDANTLEYKTRHLIDGRIIDCDQRIGIVAGYMTDE 567
                  |...|....|:   |.|..  |..:.....|:.||:.:||:.:..|||...:.||:..|
 Frog   301 ------NSRCLVAIGRLHPYITPQN--SSEVKVKPTEFVTRYTMDGKFVYVDQRATAILGYLPQE 357

  Fly   568 VRNLSPFTFMHNDDVRWVIVALRQMYDCNSSYGESTYRLFTRNGNIIYLQSKGYLEIDKETNKVH 632
            :...|.:.:.|.||...:....:.:...:.....:.|:...::|:.|.|||:.:..|:..|..:.
 Frog   358 LLGTSCYEYFHIDDYGHLTDRHKAVLQSSEKVETNCYKFRVKDGSFITLQSQWFGFINPWTKDLE 422

  Fly   633 SFVCVNTLLGEEEGKRRVQEMKKKFSVIINTQIPQSTIDVPASEHPALLEKA-----VLRLIQNL 692
            ..|.|||::................|...........:::|......||..|     :::.:.:|
 Frog   423 YIVSVNTVVPNHSSSSEDTSSLPGSSHSSQDNAKHPILNIPGMSSEILLGAANIGTQIVKEVMSL 487

  Fly   693 QKSGENGGHDDGDEDDDAQDGDDDEEDDDDDQDDGARSMSEFGDPYGSHHGRSHHGSSALSSHGH 757
            |:|  |....:||                         :|..|.|
 Frog   488 QRS--NSSPLNGD-------------------------VSPSGTP-------------------- 505

  Fly   758 GNAKTPPLALVPPEASSVKSAITKSISVVNVTAAKHLRGIHASTAVKSPSSLGSCTCSDSHSPCD 822
              .|:||...||...:.....:|.|.:.:......|  |.|. .|...|.|.    .|||:: .|
 Frog   506 --IKSPPALTVPSTTAQKGELVTLSPTEIEKLDTSH--GDHV-PAFPIPDSF----LSDSNT-LD 560

  Fly   823 F 823
            |
 Frog   561 F 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gce	NP_511160.2	bHLH_PAS	279..333	CDD:381397	22/53 (42%)
		PAS	352..>405	CDD:238075	19/53 (36%)
		PAS_11	537..646	CDD:464214	27/108 (25%)
bmal2	NP_001096298.1	bHLH_SF	73..132	CDD:469605	23/58 (40%)
		PAS	155..243	CDD:238075	26/87 (30%)
		PAS_11	329..434	CDD:464214	27/104 (26%)