Protein Alignment CG5877 and nrde2

DIOPT Version :9

• Sequence 1: NP_001259563.2
• Gene: CG5877 / 32455
• FlyBaseID: FBgn0030625
• Length: 984
• Species: Drosophila melanogaster
• Sequence 2: XP_031746460.1
• Gene: nrde2 / 780328
• XenbaseID: XB-GENE-960400
• Length: 1146
• Species: Xenopus tropicalis
• Alignment Length: 1205
• Identity: 229/1205 - (19%)
• Similarity: 418/1205 - (34%)
• Gaps: 368/1205 - (30%)

  Fly    15 AGSAKQTTKPGEEEPSTGGNWKKNESYIKKHVNIATQGPESDSSSSTEDSEDEADKRKQDDVTKT 79
            :||..|.||..:::       ||.:...|||..  .:|.:.|...:|.||:...:.|:..:....
 Frog    69 SGSDSQATKKKKKK-------KKKKKQKKKHKQ--KRGYDEDEEGNTSDSDSRPETRESKETESV 124

  Fly    80 KNVH------RGKTLEFDSSDGFYVDKVGNSSYRNIKTLKK--PARPRYKT-------RMKRLGD 129
            .::.      |..|.......|.::|:|.:.:....:..||  ||...||:       |.||.|:
 Frog   125 ASISIFSFSARQDTCVVLPGRGIWLDEVQSVTEETYRIDKKSDPANWEYKSLYQGDIARYKRKGN 189

  Fly   130 G--KYNPH------------------------------------DFSRAHSKFSLKRSRYV---- 152
            .  ..||.                                    ||.......|||...::
 Frog   190 SCLGINPKKQQINWQDALSEKKEARRKNERYFTKSTMQLLSANADFVSCKESASLKSGEFIPVLD 254

  Fly   153 --REKLIADA-------------------------PSEDEVSRL-QEQLIRTKV-----LVQQEP 184
              ::.:|:.:                         |..|.:..: ::..|..||     .:::.|
 Frog   255 PDKDGVISSSGPISWVNPLGVYDSSTALWLEGKGGPEYDTIQPVPRDNNILAKVEDYNKRIRECP 319

  Fly   185 EVLDHWLQL-----------------------HRL-LNLNLDKANRLAVAEQQIHSLETAMEHHP 225
            ..:..|::.                       ||. :.|.|:|  :||:       ||.|:|.:|
 Frog   320 NDIQLWMEFVSFQDELVKQPSMYSTSKGELDGHRTSVKLLLEK--KLAI-------LERAIESNP 375

  Fly   226 SNQQILRLYTHVANATYQANEVARRFEKMLKRNPFQYTLWSNLIMITQGDMACCNVSAVLRIYEY 290
            .:.::......:....::|..:.:.::|::..:|....||...::..||..:..:||.:..||..
 Frog   376 GSTELKLAKLKLCEEFWEAPTLLKEWQKLIFLHPNDSQLWQKYLLFCQGQFSTFSVSKMNSIYGK 440

  Fly   291 SMRRMHVGHNDEITRRFIIKETDVIMLKLFHNCLLFLRQSGHTNWMFALIRLSMELNF------- 348
            .:..:....:..:.....:.:|:..|..:|.....||||:|||..:.:|.:...:..|
 Frog   441 CLSTLAAVQDGIMLSHNALPDTESNMYDIFLQQCQFLRQAGHTEKVISLFQALTDFTFYKPDSVK 505

  Fly   349 ------------PYLTFECLQAHAGREKALIGF---------------------------EEVVL 374
                        |:  ::..:...| ||...|:                           ||:.:
 Frog   506 DMTTKEQVDFFEPF--WDSGEPRFG-EKGAKGWSSWMRQQERGGWIIINNLVEDDEDEADEELSI 567

  Fly   375 R-SGMPMPEIWTRVEQLRQAYCFLPLK-DKLASSTNVFKNKMNAERYFCSDKLVPYVHALKSQNN 437
            | ...|..:||..||..|:|..:||.: |.....|.  ....:.||....|.:.|.:..:.|...
 Frog   568 RGKNCPRYKIWLDVECSREARHWLPWRPDTTKKQTE--DECEDPERQVLFDDIGPSMFKITSPQM 630

  Fly   438 RLHLVLVVVQLMKLP------------LIRSASLADKLNPCIEDFGESEAIEMLFAAIVDRHSYA 490
            :..|....:..:.:|            .:...|:.|.::|          .|||..:
 Frog   631 QFQLFKSFLHFLGVPCGANISPRCFYLALDETSIFDHVSP----------YEMLLNS-------- 677

  Fly   491 VASLQYQFDAAMIDLAREMSVTPSYMPHLVGHKLYADT-VSNMLLKCVEVFIGEESKRRLLLILY 554
                 ::...:.|.....:. |.|.....:|:....:| :.|:....:.:..|||  :|.:.:.:
 Frog   678 -----FEIPLSGIGTVGHLD-TLSRSRQQIGYFKEGETFIQNIFQSALSLLHGEE--KRNISVWW 734

  Fly   555 LRFQ--KLLIVLH-------KSMGKLTKKFFKDKRTRMRKLINLTENRNVISFYTEQALCEIEAK 610
            |:::  |::..|.       :|.||.:|:..|       .|:....|||.::.:.|.||.|
 Frog   735 LQYEISKVVWCLQANNKKKLRSQGKRSKRLAK-------SLLKEASNRNSLALWKEYALLE---- 788

  Fly   611 HYRLG--------FSIISRIITKK--SEESSCISCVDTMHLYLVCAELHIHRGRI---------S 656
             :.||        |.....:...|  .::..|..|       |:.:||   .|::         |
 Frog   789 -WLLGNIDDARKVFDTAISLAGSKGLKDQELCSLC-------LLYSEL---EGKLLDNPEENAGS 842

  Fly   657 KAIGILVSLCLEKHAGVKQTTVYSKEQVLKGLRNAEKMVRAELKSLDTQP--AEMSLEEYF---- 715
            :|:.||.||.    .....|...|.|..:..|:..:....|....|..||  ..:||...|
 Frog   843 RAVHILTSLT----ESSPYTPYNSPEHAISILKARKVYEHAMQDCLRQQPHWGRVSLSGCFALFQ 903

  Fly   716 ----QPNKLLILLRAICLI----EVLNNRRHKEARMWLNDLQNNEFGPEAVKDSERKRFLREQIM 772
                ..:..:::||....|    |.|:|            :..|...|               :.
 Frog   904 YLTVSVDAAVVVLRQAADIPMTPETLDN------------VAQNASSP---------------LQ 941

  Fly   773 EIQMLH---LRLSFLVFGEVEFYTGFKKIKLHELLENGLEEFPRNMVFLQLWASLKSIMWHKQRS 834
            .|.::|   ||..:.|       :.:....|.::|.:.|:.:|.|   :.||.|.  |....:..
 Frog   942 AITLMHTNLLRHHYKV-------SVYPLSPLRDILMSALKTYPCN---VSLWKSY--IRTEGKLH 994

  Fly   835 RLIRTKAGIASLAHLVVAI----------HNRFGIVDTNDKFSKEATRKM-----VCNRLVSIVE 884
            ...|.:..|.|:..:..|:          .:|..||::..:..:.....:     :.||:.::.|
 Frog   995 NASRVRRFIDSIRRMTPALEPCLFAIRAEEDRKKIVESVQRPDQGEVHSIFPETGLSNRIKALFE 1059

  Fly   885 TFLPTNLDRLDVEEEHYRILRRNSIYWRLY---MIALSKTNASFRRSKEVLIMAMDECPWDKSLL 946
            ..|.:...            .|..:.||||   |::|...    .|||.:...|:..|||.|:|.
 Frog  1060 YALQSEYG------------SRCPLLWRLYLHFMVSLGNK----ERSKGLFYKAIQSCPWAKALY 1108

  Fly   947 MEGAKVLPVKLASLQDLMTEKEIRIFAMPEEVDVL 981
            ::..:..|.:|....|||||||:|:....||:|:|
 Frog  1109 LDAVEYFPEQLQETIDLMTEKELRVRVPLEELDLL 1143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5877	NP_001259563.2	NRDE-2	180..>348	CDD:285605	36/191 (19%)
nrde2	XP_031746460.1	NRDE2_MID	159..254	CDD:412062	17/94 (18%)
		NRDE-2	310..643	CDD:400637	62/346 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D231700at33208
OrthoFinder	1	1.000	-	-		FOG0003950
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4981
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010