Protein Alignment CG5877 and LOC1272483

DIOPT Version :10

• Sequence 1: NP_573014.2
• Gene: CG5877 / 32455
• FlyBaseID: FBgn0030625
• Length: 984
• Species: Drosophila melanogaster
• Sequence 2: XP_061515234.1
• Gene: LOC1272483 / 1272483
• VectorBaseID: AGAMI1_004761
• Length: 1007
• Species: Anopheles gambiae
• Alignment Length: 1118
• Identity: 291/1118 - (26%)
• Similarity: 479/1118 - (42%)
• Gaps: 249/1118 - (22%)

  Fly     1 MSLFPAYGAGRTSAAGSAKQTTKP--GEEEPSTGG----NWKKNESYIK---KHVNIATQGPESD 56
            |||||||             .|:|  .:.||:...    .|..|:|:|:   |..|..|:...|.
Mosquito     1 MSLFPAY-------------NTEPLVAKSEPTASAPSELAWLTNQSFIRFGTKQTNDETESENSA 52

  Fly    57 SSSSTEDSEDEADKRKQDDVTK--------------------TKNVHRGKTLEFDSSD------- 94
            ..:..::..|.||:..:.|..|                    :|..|...:.....|:
Mosquito    53 PKTPDDNQSDIADEECRPDTAKDSKPSKRHRSKHKKKRKKKHSKRRHGSSSSSSPESETEKQKCT 117

  Fly    95 ---------------GFYVDKVGNSSYRNIKTLKKPARPRYK-TRMKRLGDGKYNPHDFSRAHSK 143
                           .:|.|......|..::.|.:||.|||: ..:..|| .::|.....|...|
Mosquito   118 AVAIPAPSAVRVSEVDYYTDVDPLKIYLTVEKLHRPACPRYRLVTLNPLG-VRFNGKGSGRERYK 181

  Fly   144 FSLKRSRYVRE--------KLIADAPSEDEVSRLQEQLIRTKVLVQQEPEVLDHWLQLHRLLN-- 198
                  ||.|.        |......:::|:...:.:|.|:   ::.| |.:|.|::|.|...
Mosquito   182 ------RYYRTVKAKEREGKAHTGKEAQEEIFAREAELERS---IRAE-ETVDKWIELVRYRQDH 236

  Fly   199 -LNLDKANRLAVAEQQIHSLETAMEHHPSNQQILRLYTHVANATYQANEVARRFEKMLKRNPFQY 262
             ::.|....   .::::..:|.|....|.::::|:||.......:..:||.....:.:.::....
Mosquito   237 PIHFDSYQN---HKRELSLIERARRQFPYDEKLLQLYLEAIVQVHPTDEVLNLIRRAITKDETNV 298

  Fly   263 TLWSNLIMITQGDMACCNVSAVLRIYEYSMRRMHVGHNDEITRRFIIKETDVIMLKLFHNCLLFL 327
            |||.:||...|..||.|.|..||::||.|.|.:           |:.:.:|..||:||.||..|.
Mosquito   299 TLWRSLIRNKQCAMAQCIVPDVLKLYEKSTRSL-----------FMARRSDETMLQLFRNCATFC 352

  Fly   328 RQSGHTNWMFALIR--LSMELNFPYLTFECLQAHAGREKALIGFEEVVLRSGMPMPEIWTRVEQL 390
            ||:|....||.:::  |||.::..|.| :...|.....:.||.:||::|:||:||.|||.|||||
Mosquito   353 RQAGLCELMFGMVQHALSMNVSGRYGT-DGTFASPEHFQQLIEYEELILKSGLPMNEIWLRVEQL 416

  Fly   391 RQAYCFLPLK-DKLASSTNVFKNKMNAERYFCSDKLVPYVHALKSQNNRLHLVLVVVQLMKLPLI 454
            |.|:.:||.: .:|||         :.:|...:|.:|.:|:.|.::.....|.|..::|||.|..
Mosquito   417 RTAFHYLPFEGGRLAS---------DPQRMVLTDDVVGFVYPLINKTRAFELTLTALKLMKFPFR 472

  Fly   455 RSASLADKLNPCIEDFGESEAIEM--------LFAAIV-DRHSYAVASLQYQFDAAMIDLAREMS 510
            |.   .|:         |.||.||        :|..:. ||          ..|.::....:::|
Mosquito   473 RQ---YDR---------EVEAYEMDYPEQLLPIFLDVFRDR----------TLDGSLYAFIKQLS 515

  Fly   511 VTPSYMPHLVGHKLYADTVSNMLLKCVEVFIGEESKRRLLLILYLRFQKLLIVLHKSMGKLTKKF 575
            |.|||:...:.|:.|.:.|...|...::.|.|.||  .:||.|||:.:::|:...|::....|..
Mosquito   516 VAPSYIRANIAHESYLELVRKSLALAIDHFTGTES--AVLLTLYLQLERILVCEGKALSAGRKSI 578

  Fly   576 FKDK-----RTRMRKLINLTE--NRNVISFYTEQALCEIEAKHYRLGFSIISRIITKKSEESSCI 633
            .::.     |.|::.|:..|.  |:|.:..|.|..|.|.|    ..|.|:..|.|...|.:..|.
Mosquito   579 LEEAQAKAVRARVKHLLKHTHSTNQNSLPVYAEYGLLEYE----MTGLSVACRKIFSTSVQVFCS 639

  Fly   634 S---------------CVDTMHLYLVCAELHIHRGRISKAIGILVSLCLEKH----------AGV 673
            |               ..|..||.|...||.:..|:..:||..|.:|.|::|          ..|
Mosquito   640 SEQAAPPSGDDDTQEDDNDLFHLVLTVVELLLLEGQKDEAIQTLTNLALKRHELTFETTATTPTV 704

  Fly   674 KQTTVYSKEQVLKGLRNAEKMVRAELKSLDTQP-AEMS--LEEYFQPNKLLILLRA----ICLIE 731
            ..||..|..|  |......:.||||     :|| .|::  .|.:|..:.|:..::|    :.||.
Mosquito   705 PDTTKLSALQ--KFSDRVNRAVRAE-----SQPDTELNPRTEHHFLVHPLITSIKAYVTYLALIR 762

  Fly   732 VLNNRRHKEARMWL---NDLQNNEFGPEAVKDSERKRFLREQIMEIQMLHLRLSFLVFGEVEFYT 793
            ...:...|:...:|   ||..|           .|:|.||||:.||        :|...|:..:
Mosquito   763 SNLSEATKQLETFLYLFNDPTN-----------ARQRLLREQLFEI--------YLQLFEIARH- 807

  Fly   794 GFKKI----------KLHELLENGLEEFPRNMVFLQLWASLKSIMWHKQRSRLIRTKAGIASLAH 848
            |.|:.          .|.:|::..|.|||.|:..|:|.....::.|.:.|..|.:.....|.|..
Mosquito   808 GRKQAHQPPPAEGLRSLLDLVDRTLNEFPANLYALRLVVFNDNLPWLRLRGVLGKHLTPQAVLLL 872

  Fly   849 LVVAIHNRFGIVDTNDKF-SKEAT--RKMVCNRLVSIVETFLPTNLDRLDVEEEHYRILRRNSIY 910
            ::.|.:......:|.|.| :.||:  ::.:.|.|...:::   |:.|..       .:|.||::.
Mosquito   873 VIAARYREACTAETLDDFIATEASPYKQRILNLLGGALKS---TSTDSA-------AVLYRNALL 927

  Fly   911 WRLYMIAL-SKTNAS-----FRRSKEVLIMAMDECPWDKSLLMEGAKVLPVKLASLQDLMTEKEI 969
            ||||:..| .:.||.     ..:.:..|.:|::.|||:|:|.::||...|.:|:.|.|||.||::
Mosquito   928 WRLYLRELFDQPNAPPGYSVLEQCRRTLYVALEACPWNKALYLDGASCAPQELSQLLDLMMEKQL 992

  Fly   970 RIFAMPEEVDVLR 982
            |:.|:|||:.:||
Mosquito   993 RVHAIPEELAILR 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5877	NP_573014.2	NRDE-2	180..>348	CDD:462472	48/172 (28%)
LOC1272483	XP_061515234.1	None