DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5662 and FAXC

DIOPT Version :9

Sequence 1:	NP_001285266.1	Gene:	CG5662 / 32450	FlyBaseID:	FBgn0030620	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_115900.1	Gene:	FAXC / 84553	HGNCID:	20742	Length:	409	Species:	Homo sapiens

Alignment Length:	291	Identity:	68/291 - (23%)
Similarity:	113/291 - (38%)	Gaps:	57/291 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KSEEAWPADA-HLHQPAEANQLLLPERSSCLAVKTFLRMCNLPFTEHISDNAEFMSPGGRLT--- 80
            |.:|....|| .|||.|..|..:......||.::|:|||.:||:..:.         ||:|:
Human    90 KQQEIDSKDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYF---------GGKLSAQG 145

  Fly    81 HLPLLRLGPVK-TFAEFEPIVAQVEAVQGGNCLDSWMSEDQRDNIRCLVSYVENVFTLAEIHMSF 144
            .:|.:.....| :..||  |:..:|...|.| |:..:...:|...|.:...||..|.....:..:
Human   146 KMPWIEYNHEKVSGTEF--IIDFLEEKLGVN-LNKNLGPHERAISRAVTKMVEEHFYWTLAYCQW 207

  Fly   145 VDEVNYQLYTATRCAAAHPWPLSTIRRFAKQKDAQKILK-------VYRWQDLDNDQVIQEVSIC 202
            ||.:|   .|....:.:...|.|.:.|:......:.|:|       :.|:.:.:...::::....
Human   208 VDNLN---ETRKMLSLSGGGPFSNLLRWVVCHITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRS 269

  Fly   203 ADALIAELEEDQAKSYFGGSRPCKLDALVFGHVVAIMTTKLPNMELAAVLATYP---------RL 258
            ...|:.:      |.|..|.:...|||.||||:...|.| ||        .|.|         .|
Human   270 LAGLLGD------KKYIMGPKLSTLDATVFGHLAQAMWT-LP--------GTRPERLIKGELINL 319

  Fly   259 LAHCRRIDQSLF------DGKLLTSAVEEQE 283
            ..:|.||.:..:      |...:..:.|..|
Human   320 AMYCERIRRKFWPEWHHDDDNTIYESEESSE 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5662	NP_001285266.1	GST_N_Metaxin2	29..106	CDD:239377	23/81 (28%)
CG5662	NP_001285266.1	GST_C_Metaxin2	138..266	CDD:198320	30/143 (21%)
FAXC	NP_115900.1	GST_N_4	117..212	CDD:379936	27/106 (25%)
		GST_C_6	263..326	CDD:379935	19/77 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	372..409
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910