Protein Alignment CG5662 and MTX1

DIOPT Version :10

• Sequence 1: NP_573009.1
• Gene: CG5662 / 32450
• FlyBaseID: FBgn0030620
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_002446.3
• Gene: MTX1 / 4580
• HGNCID: 7504
• Length: 466
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 71/313 - (22%)
• Similarity: 115/313 - (36%)
• Gaps: 46/313 - (14%)

  Fly     3 LEQNLTAALMQSSAEEGKSE---EAWPADAHLHQPAEANQLLLPERSSC--------------LA 50
            |...:..|:......:|::|   |.:|..       ...::..|....|              ||
Human   117 LTATIGGAVAGGGPRQGRAEAHKEVFPGQ-------RVGKMAAPMELFCWSGGWGLPSVDLDSLA 174

  Fly    51 VKTFLRMCNLPFTEHISDNAEFMSPGGRLTHLPLLRLGPVKTFAEFEPIVAQVEAVQGGNCLDSW 115
            |.|:.|....|...|...| .:.||.|.   ||.||....:..:....|:..:...:.....|
Human   175 VLTYARFTGAPLKVHKISN-PWQSPSGT---LPALRTSHGEVISVPHKIITHLRKEKYNADYD-- 233

  Fly   116 MSEDQRDNIRCLVSYVENVFTLAEIHMSFVDEVNYQLYTATRCAAAHPWPLSTIRRFAKQKDAQK 180
            :|..|..:....:|.:|.......:|..::|..||...|....|.|.|:||:.......|:...:
Human   234 LSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYME 298

  Fly   181 ILKVYRWQDLDND------QVIQEVSICADALIAELEEDQAKSYFGGSRPCKLDALVFGHVVAIM 239
            .|::...:....|      ::.:|...|...|...|   .::.:|.|..|..|||.||.::..::
Human   299 RLQLLTGEHRPEDEEELEKELYREARECLTLLSQRL---GSQKFFFGDAPASLDAFVFSYLALLL 360

  Fly   240 TTKLPNMELAAVLATYPRLLAHCRRIDQSLF--DG-----KLLTSAVEEQEDE 285
            ..|||:.:|...|.....|.|:|..|....|  ||     :..|.|..|.|:|
Human   361 QAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEE 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5662	NP_573009.1	GST_N_Metaxin2	29..106	CDD:239377	18/90 (20%)
		GST_C_Metaxin2	138..266	CDD:198320	33/133 (25%)
MTX1	NP_002446.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		2/15 (13%)
		Tom37	172..293	CDD:463150	31/126 (25%)
		GST_C_Metaxin1_3	255..391	CDD:198321	34/138 (25%)