DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5662 and CG8004

DIOPT Version :9

Sequence 1:	NP_001285266.1	Gene:	CG5662 / 32450	FlyBaseID:	FBgn0030620	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_649161.1	Gene:	CG8004 / 40178	FlyBaseID:	FBgn0036920	Length:	269	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	126/273 - (46%)
Similarity:	175/273 - (64%)	Gaps:	11/273 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LEQNLTAALMQSSAEEGKSEEAWPADAHLHQPAEANQLLLPERSSCLAVKTFLRMCNLPFTEHIS 67
            |.|.:||        :..|.|.||.||.|:||.||.|:||||.:||||||.:|:||||||.....
  Fly     6 LSQLITA--------DKLSAEPWPEDATLYQPYEAEQILLPENASCLAVKAYLKMCNLPFLIRSC 62

  Fly    68 DNAEFMSPGGRLTHLPLLRLGPVKTFAEFEPIVAQVEAVQGGNCLDSWMSEDQRDNIRCLVSYVE 132
            .|||.||||||:|.||.:|.|.. .||||||||..||  |....:.||..||::.::|..||.||
  Fly    63 ANAEHMSPGGRMTKLPFIRAGAF-IFAEFEPIVNFVE--QKELAIGSWQDEDEKADMRTYVSLVE 124

  Fly   133 NVFTLAEIHMSFVDEVNYQLYTATRCAAAHPWPLSTIRRFAKQKDAQKILKVYRWQDLDNDQVIQ 197
            |:||:||:::||.:|..|:..||.|.....||||:.::.:.|:::|.::||||:|.|||.|.||.
  Fly   125 NIFTMAELYISFKNERVYKEVTAPRNGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVID 189

  Fly   198 EVSICADALIAELEEDQAKSYFGGSRPCKLDALVFGHVVAIMTTKLPNMELAAVLATYPRLLAHC 262
            :|:.|.:.|..:|:|.....:|.|.:||:|||:.|||:.:|:||.||||.||..:..:..|:..|
  Fly   190 KVAKCCETLEYKLKESPETPFFYGDQPCELDAIAFGHLFSILTTTLPNMALAQTVQKFQHLVEFC 254

  Fly   263 RRIDQSLFDGKLL 275
            |.:|:..|..:.|
  Fly   255 RFVDEKYFQTRCL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5662	NP_001285266.1	GST_N_Metaxin2	29..106	CDD:239377	48/76 (63%)
CG5662	NP_001285266.1	GST_C_Metaxin2	138..266	CDD:198320	53/127 (42%)
CG8004	NP_649161.1	GST_N_Metaxin2	24..100	CDD:239377	48/78 (62%)
CG8004	NP_649161.1	GST_C_Metaxin2	130..258	CDD:198320	53/127 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469152
Domainoid	1	1.000	99	1.000	Domainoid score	I7032
eggNOG	1	0.900	-	-		E1_KOG3027
Homologene	1	1.000	-	-		H4777
Inparanoid	1	1.050	205	1.000	Inparanoid score	I3700
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52965
OrthoDB	1	1.010	-	-		D1219712at2759
OrthoFinder	1	1.000	-	-		FOG0005469
OrthoInspector	1	1.000	-	-		otm25675
orthoMCL	1	0.900	-	-		OOG6_105112
Panther	1	1.100	-	-	P	PTHR12289
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3890
	13	12.810