DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5662 and MTX3

DIOPT Version :9

Sequence 1:	NP_001285266.1	Gene:	CG5662 / 32450	FlyBaseID:	FBgn0030620	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001350747.1	Gene:	MTX3 / 345778	HGNCID:	24812	Length:	312	Species:	Homo sapiens

Alignment Length:	275	Identity:	66/275 - (24%)
Similarity:	105/275 - (38%)	Gaps:	52/275 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LPE-RSSCLAVKTFLRMCNLPFTEHISDNAEFMSPGGRLTHLPLLR---------------LGPV 90
            ||. .|..|.|..:.:....|...::.||....|.|    .:|:|.               |...
Human    16 LPSVHSESLVVMAYAKFSGAPLKVNVIDNTWRGSRG----DVPILTTEDDMVSQPAKILNFLRKQ 76

  Fly    91 KTFAEFEPIVAQVEAVQGGNCLDSWMSEDQRDNIRCLVSYVENVFTLAEIHMSFVDEVNYQLYTA 155
            |..|::|     :.|.||.:.|             ..::.:|.....|.:|..:|:..||...|.
Human    77 KYNADYE-----LSAKQGADTL-------------AYIALLEEKLLPAVLHTFWVESDNYFTVTK 123

  Fly   156 TRCAAAHPWPLSTIRRFAKQKDA-QKIL------KVYRWQDLDNDQVIQEVSICADALIAELEED 213
            ...|:..|:|||.|......|.| .:||      .:|..:::: .|:.::...|.:.|...|...
Human   124 PWFASQIPFPLSLILPGRMSKGALNRILLTRGQPPLYHLREVE-AQIYRDAKECLNLLSNRLGTS 187

  Fly   214 QAKSYFGGSRPCKLDALVFGHVVAIMTTKLPNMELAAVLATYPRLLAHCRRIDQSLFDGKL--LT 276
            |   :|.|..|..|||.|||.:..:...:.|.::|...|.....|...|..|..|.|...|  ::
Human   188 Q---FFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLKQLSNLCRFCDDILSSYFRLSLGGIS 249

  Fly   277 SAVEEQEDEMELEKI 291
            .|.:|..| ..|:|:
Human   250 PAGQETVD-ANLQKL 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5662	NP_001285266.1	GST_N_Metaxin2	29..106	CDD:239377	16/79 (20%)
CG5662	NP_001285266.1	GST_C_Metaxin2	138..266	CDD:198320	36/134 (27%)
MTX3	NP_001350747.1	Tom37	23..142	CDD:371142	30/140 (21%)
		GST_C_Metaxin1_3	105..241	CDD:198321	38/139 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	278..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422112at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920