DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5662 and Mtx2

DIOPT Version :9

Sequence 1:	NP_001285266.1	Gene:	CG5662 / 32450	FlyBaseID:	FBgn0030620	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001008287.1	Gene:	Mtx2 / 288150	RGDID:	1306473	Length:	263	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	90/251 - (35%)
Similarity:	141/251 - (56%)	Gaps:	9/251 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EAWPADAHLHQPAEANQLLLPERSSCLAVKTFLRMCNLPFTEHISDNAEFMSPGGRLTHLPLLRL 87
            |.||.:|.|:|.....|:||.:.::.|||:|||:|||||.......|||:|||.|:   :|.:.:
  Rat    16 EPWPENATLYQQLRGEQILLSDNAASLAVQTFLQMCNLPVKVVCRANAEYMSPSGK---VPFIHV 77

  Fly    88 GPVKTFAEFEPIVAQVEAVQGGNCLDSWMSEDQRDNIRCLVSYVENVFTLAEIHMSFVDEVNYQL 152
            |. :..:|..||:..|:|  .|:.|...:.|.|:..::..:..|.|:...||:::.:.||.....
  Rat    78 GN-QVVSELGPIIQFVKA--KGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGE 139

  Fly   153 YTATRCAAAHPWPLSTIRRFAKQKDAQKILKVYRWQDLDNDQVIQEVSICADALIAELEEDQAKS 217
            .|..|..:.:||||:.|..:.||.:.::.:|...|.:...|||:::|..|..||...|   ..:.
  Rat   140 ITLARYGSPYPWPLNLILTYQKQCEVKRKMKAIGWGNKTLDQVLEDVDRCCQALSQRL---GTQP 201

  Fly   218 YFGGSRPCKLDALVFGHVVAIMTTKLPNMELAAVLATYPRLLAHCRRIDQSLFDGK 273
            ||...:|.:||||||||:..|:||:|.:.||...:..|..|||.||||:|..|:.:
  Rat   202 YFFDKQPTELDALVFGHLYTILTTQLTSDELCEKVKNYSNLLAFCRRIEQDYFEDR 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5662	NP_001285266.1	GST_N_Metaxin2	29..106	CDD:239377	30/76 (39%)
CG5662	NP_001285266.1	GST_C_Metaxin2	138..266	CDD:198320	47/127 (37%)
Mtx2	NP_001008287.1	GST_N_Metaxin2	22..95	CDD:239377	31/78 (40%)
		GstA	33..251	CDD:223698	81/226 (36%)
		GST_C_Metaxin2	125..250	CDD:198320	47/127 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353111
Domainoid	1	1.000	104	1.000	Domainoid score	I6565
eggNOG	1	0.900	-	-		E1_KOG3027
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4777
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3535
OMA	1	1.010	-	-		QHG52965
OrthoDB	1	1.010	-	-		D1219712at2759
OrthoFinder	1	1.000	-	-		FOG0005469
OrthoInspector	1	1.000	-	-		otm44729
orthoMCL	1	0.900	-	-		OOG6_105112
Panther	1	1.100	-	-	O	PTHR12289
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3890
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770