DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5662 and mtx2

DIOPT Version :9

Sequence 1:	NP_001285266.1	Gene:	CG5662 / 32450	FlyBaseID:	FBgn0030620	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_997740.1	Gene:	mtx2 / 286741	ZFINID:	ZDB-GENE-021210-2	Length:	274	Species:	Danio rerio

Alignment Length:	283	Identity:	97/283 - (34%)
Similarity:	154/283 - (54%)	Gaps:	32/283 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MQSSAEEGKSE----EAWPADAHLHQPAEANQLLLPERSSCLAVKTFLRMCNLPFTEHISDNAEF 72
            |..:||...|:    |.||.:|.|:||.:.:|:||.:.:|.|||:||||||.||.......|||:
Zfish     1 MSLAAEAFVSQIAAAEPWPENAALYQPLKEDQILLSDSASSLAVQTFLRMCGLPVQVSCRANAEY 65

  Fly    73 MSPGGRLTHLPLLRLGPVKTFAEFEPIVAQVEAVQGGNCLDSWMSEDQRDNIRCLVSYVENVFTL 137
            |||.|:   :|.:::|. :..:|..|||...:|  .|:.|...:.:.||..::..:..|.|:...
Zfish    66 MSPSGK---VPFIQVGN-QVVSELGPIVQFTKA--KGHSLSDGLDDVQRAEMKAYMELVNNMLLT 124

  Fly   138 AEIHMSFVDEVNYQLYTAT-----RCAAAHPWPLSTIRRFAKQKDAQKILKVYRWQDLDNDQVIQ 197
            ||:::.:.|:     :|||     |.::.:.|||:.|..:.||.:.::.:....|.....:||.:
Zfish   125 AELYIQWCDD-----FTATEISRPRYSSPYSWPLNHILAYQKQWEVRRKMNAIGWSGKSLEQVYE 184

  Fly   198 EVSICADALIAELEEDQAKSYFGGSRPCKLDALVFGHVVAIMTTKLPNMELAAVLATYPRLLAHC 262
            :||.|..||...|   ..:.||...:|.:||||||||:..|:||:|.:.||...:.:|..||:.|
Zfish   185 DVSQCCQALSQRL---GTQPYFFNKQPTELDALVFGHLFTILTTQLTSDELVEKVKSYSNLLSFC 246

  Fly   263 RRIDQSLFDGKLLTSAVEEQEDE 285
            .||:|:.|         :|||.|
Zfish   247 HRIEQAYF---------KEQERE 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5662	NP_001285266.1	GST_N_Metaxin2	29..106	CDD:239377	32/76 (42%)
CG5662	NP_001285266.1	GST_C_Metaxin2	138..266	CDD:198320	44/132 (33%)
mtx2	NP_997740.1	GST_N_Metaxin2	22..95	CDD:239377	33/78 (42%)
		GstA	33..260	CDD:223698	84/249 (34%)
		GST_C_Metaxin2	125..250	CDD:198320	44/132 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595154
Domainoid	1	1.000	99	1.000	Domainoid score	I7032
eggNOG	1	0.900	-	-		E1_KOG3027
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4777
Inparanoid	1	1.050	205	1.000	Inparanoid score	I3700
OMA	1	1.010	-	-		QHG52965
OrthoDB	1	1.010	-	-		D1219712at2759
OrthoFinder	1	1.000	-	-		FOG0005469
OrthoInspector	1	1.000	-	-		otm25675
orthoMCL	1	0.900	-	-		OOG6_105112
Panther	1	1.100	-	-	O	PTHR12289
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3890
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770