DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9095 and SELL

DIOPT Version :9

Sequence 1:	NP_001096984.1	Gene:	CG9095 / 32447	FlyBaseID:	FBgn0030617	Length:	1141	Species:	Drosophila melanogaster
Sequence 2:	NP_000646.3	Gene:	SELL / 6402	HGNCID:	10720	Length:	372	Species:	Homo sapiens

Alignment Length:	346	Identity:	82/346 - (23%)
Similarity:	135/346 - (39%)	Gaps:	92/346 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 LASYNGKCYIF-YNRQPLNFLDALSFCRSRGGTLISESNPALQGFISWEL-WRRHRSDVSSQYWM 316
            ||.:...|:.: |:.:|:|:..|..|||.....|::..|.|...::...| :.|      |.||:
Human    31 LAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSR------SYYWI 89

  Fly   317 GAVRDGSDRSSWKWVNGDELTVSFWSHPGGD---------EDCARF------DGSKGWLWSDTNC 366
            |..:.|   ..|.|| |...:::..:...||         |||...      |..|   |:|..|
Human    90 GIRKIG---GIWTWV-GTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGK---WNDDAC 147

  Fly   367 NTLLNFIC---QHQPKTC-GRPEQPPNSTMVALNGFEVGAQIKYSCDANHLLVGPATRTCLETGF 427
            :.|...:|   ..||.:| |..|     .:..:|        .|:|:.             :.|:
Human   148 HKLKAALCYTASCQPWSCSGHGE-----CVEIIN--------NYTCNC-------------DVGY 186

  Fly   428 YNEFPPVCKYI--------------ECGLPASIAHGSYALLNNTVGYLSLVKYSCEEGYEMIGRA 478
            |.   |.|:::              :|..|.    |:::       :.|...:||.||..:.|..
Human   187 YG---PQCQFVIQCEPLEAPELGTMDCTHPL----GNFS-------FSSQCAFSCSEGTNLTGIE 237

  Fly   479 LLTCDFDERWNGPPPRCEIVECDTLPGNYYSTIINA--PNGTY-YGSKAEISCPPGYRMEGPRVL 540
            ..||.....|:.|.|.|::::|:.|...... |:|.  |..:: :.|.....|..|..:.|.:..
Human   238 ETTCGPFGNWSSPEPTCQVIQCEPLSAPDLG-IMNCSHPLASFSFTSACTFICSEGTELIGKKKT 301

  Fly   541 TCLASGQWSSALPRCIKLEPS 561
            .|.:||.||:..|.|.||:.|
Human   302 ICESSGIWSNPSPICQKLDKS 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9095	NP_001096984.1	CCP	37..93	CDD:153056
		FTP	94..242	CDD:128870
		CLECT	256..375	CDD:214480	34/138 (25%)
		Sushi	381..435	CDD:278512	9/54 (17%)
		CCP	440..496	CDD:153056	14/55 (25%)
		CCP	500..556	CDD:153056	15/58 (26%)
SELL	NP_000646.3	CCP	197..255	CDD:153056	14/68 (21%)
		CCP	259..317	CDD:153056	15/58 (26%)
		CLECT_selectins_like	39..157	CDD:153062	33/130 (25%)
		EGF_CA	<165..192	CDD:238011	9/55 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11997
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.970