DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG9095 and SELE

DIOPT Version :9

Sequence 1:NP_001096984.1 Gene:CG9095 / 32447 FlyBaseID:FBgn0030617 Length:1141 Species:Drosophila melanogaster
Sequence 2:NP_000441.2 Gene:SELE / 6401 HGNCID:10718 Length:610 Species:Homo sapiens


Alignment Length:373 Identity:87/373 - (23%)
Similarity:145/373 - (38%) Gaps:84/373 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   256 SYNGKCYIFYNRQPLNFLDALSFCRSRGGTLISESNPA----LQGFISWELWRRHRSDVSSQYWM 316
            |||      .:.:.:.:.:|.::|:.|...|::..|..    |...:|:.         .|.||:
Human    23 SYN------TSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYS---------PSYYWI 72

  Fly   317 GAVRDGSDRSSWKWVNGDE-LT--VSFWSHPG------GDEDCARF----DGSKGWLWSDTNCN- 367
            | :|  ...:.|.||...: ||  ...|: ||      .||||...    :...| :|:|..|: 
Human    73 G-IR--KVNNVWVWVGTQKPLTEEAKNWA-PGEPNNRQKDEDCVEIYIKREKDVG-MWNDERCSK 132

  Fly   368 ------------------------TLLNFICQHQP----------KTCGRPEQPPNSTMVA---L 395
                                    |:.|:.|:..|          ..|...|.|.:.::|.   |
Human   133 KKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPL 197

  Fly   396 NGFEVGAQIKYSCDANHLLVGPATRTCLETGFYNEFPPVCKYIECGLPASIAHGSYALLNN--TV 458
            ..|...:....|||..:|.....|..|:.:|.::...|.|..:||....:.|:|......|  :.
Human   198 GNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSF 262

  Fly   459 GYLSLVKYSCEEGYEMIGRALLTCDFDERWNGPPPRCEIVECDTL--PGNYYSTIINAPNGTY-Y 520
            .:.:...:.||||:|::|...|.|.....|:...|.|:.|.|..:  |.|......::|.|.: :
Human   263 PWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTF 327

  Fly   521 GSKAEISCPPGYRMEGPRVLTCLASGQWSSALPRCIKLEPSTQPTAAS 568
            .|....:|..|:.::||..:.|...|||:..:|.|    .:.|.||.|
Human   328 KSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVC----EAFQCTALS 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9095NP_001096984.1 CCP 37..93 CDD:153056
FTP 94..242 CDD:128870
CLECT 256..375 CDD:214480 33/160 (21%)
Sushi 381..435 CDD:278512 14/56 (25%)
CCP 440..496 CDD:153056 14/57 (25%)
CCP 500..556 CDD:153056 15/58 (26%)
SELENP_000441.2 CLECT_selectins_like 22..140 CDD:153062 31/136 (23%)
Carbohydrate binding. /evidence=ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY 101..109 0/7 (0%)
Carbohydrate binding. /evidence=ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY 113..118 0/4 (0%)
Carbohydrate binding. /evidence=ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY 126..128 0/1 (0%)
EGF_CA <148..175 CDD:238011 4/26 (15%)
CCP 199..425 CDD:332582 47/177 (27%)
CCP 333..547 CDD:332582 14/43 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 47 1.000 Domainoid score I11997
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19325
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
44.060

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