DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9095 and Cr2

DIOPT Version :9

Sequence 1:	NP_001096984.1	Gene:	CG9095 / 32447	FlyBaseID:	FBgn0030617	Length:	1141	Species:	Drosophila melanogaster
Sequence 2:	XP_008768069.1	Gene:	Cr2 / 289395	RGDID:	1310065	Length:	1406	Species:	Rattus norvegicus

Alignment Length:	892	Identity:	186/892 - (20%)
Similarity:	275/892 - (30%)	Gaps:	349/892 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 CSFPGSPAHSSVVFSNANLTQGTVASYSCERGFELLGPARRVC---DKGQWVPEGIPFCVLNVAA 98
            |..|..|.|.| |..|..:|.|:..:|||.:|:.|:|.:...|   |........:|.|.|  ..
  Rat    83 CMNPQEPLHGS-VHINTGITFGSTITYSCNKGYRLIGDSSATCIISDNTVMWDNSVPICEL--IP 144

  Fly    99 GKAPMQISTDGAGAPQKAIDGSTSAFF----TPETCSLTK---------AERSPW---------- 140
            .::|..||.   |..|.:   |..:||    ....|.:.|         .|:|.:
  Rat   145 CESPPAISN---GYFQSS---SRDSFFYGMVATYYCHVGKNREKLFDLVGEKSIYCTSKDNQVGI 203

  Fly   141 WYVNLLEPYMVQLVR-----LDFGKSCCGNKPA-----TIVVRVGNN-----------RPDLGTN 184
            |  |...|..:..|:     ::.|....|.||:     |::.:..:.           :||...:
  Rat   204 W--NSPPPQCIARVKCPMPEIENGDVESGFKPSFFLNDTVMFKCKSGFIMKGSSIVWCQPDSKWS 266

  Fly   185 ---PICNRFTGLL------------------EAGQPLFLPCNPPMPGAFVSVHLENSTP----NP 224
               |.|  |.|.|                  ..||.:...|.|..  ..:..:|...||    :|
  Rat   267 PPLPTC--FRGCLPPQNILHGDYNEKDKEFFSVGQKVSYSCEPGY--TLIGTNLVECTPLGAWSP 327

  Fly   225 -LSICEAFVYTDQALPIERCPTFRDQPPGALASYNGKCYIFYNRQ---PLNFLDALSF------- 278
             :..||          ::.|    |..|..|  .||:..:.:|.|   .::|:..|.|
  Rat   328 SVPTCE----------VKSC----DAIPNQL--LNGRVLLPHNLQLGAEVSFVCDLGFQLKGKSS 376

  Fly   279 --CRSRGGTLI----------------SESN---------PALQGFI------------------ 298
              |...|.|:|                .|.|         |.|.|.:
  Rat   377 SQCVPEGETVIWNNKFPVCEQLSCDPPPEVNNTRRLYYSLPVLPGTVVRYTCLPGYRLIGEKAIF 441

  Fly   299 ---------SW-------ELWRRHRSDVSSQYWMGAVRDGSDRSSWKWVNGDELTVSFWSHPGGD 347
                     :|       |.|.: .|..|.....|.:.:...|..:|  :||.:||:
  Rat   442 CISKDQVTATWDKATPICEPWNK-MSACSKPIVPGGIINPGSRPPFK--HGDSVTVT-------- 495

  Fly   348 EDC-ARF--DGSKG-W-----LWSDTNCNTLLNFICQHQ-PKTCGRPEQPP----NSTMVALNGF 398
              | |.|  .|||. |     :|..|...     :|:.. |..|  |..|.    :.|...:..|
  Rat   496 --CKANFTMKGSKTVWCRANKMWGPTPLP-----VCESDFPLEC--PSLPTIHNGHHTGQHVEKF 551

  Fly   399 EVGAQIKYSCDANHLLVGPATRTCLETGFYNEFPPVCKYIECGLPASIAHGSY----ALLNNTVG 459
            ..|..:.|||:..:||||..|..||.:|.:::..|.||..:|..|..:.:|..    :|...|..
  Rat   552 VAGLSVTYSCEPGYLLVGKKTIKCLSSGAWDDVIPTCKEAKCERPEKLPNGQVKEPPSLRVGTTV 616

  Fly   460 YLSLVKYSCEEGYEMIGRALLTCDFDER------------------------------------- 487
            |     :||.||||:.|:....|...|:
  Rat   617 Y-----FSCNEGYELQGQPSSKCVIVEQKAVWTKKPVCKEILCPPPPPVLNGRHSGRFSGNVPYG 676

  Fly   488 ------------------------------------WNGPPPRCE--IVECDTL-PGNYYSTIIN 513
                                                |:||.|.|:  |.|...| |......|::
  Rat   677 NNVTYMCDPSPEKGVNFTLIGEKTIYCTNSSEKTGIWSGPAPYCKLSISEAQCLRPQINRGQILS 741

  Fly   514 APNGTY-YGSKAEISCPPGYRMEGPRVLTCLASGQWSSALPRC--------------------IK 557
            ....:| |......||.||:.::|...:.|.|.|.|...:|.|                    :.
  Rat   742 ILKESYSYNDTVAFSCEPGFTLKGSGRIRCSAQGTWKPPVPVCEKGCQAPPKIINGQKEDRYFLN 806

  Fly   558 LEPST--------------QPTAAST-------IPVPSSVATPPPFRPKVVSSTTSRTPYRPAV- 600
            .:|.|              :.|...|       ||....||...|..|.|.....:.. .|||:
  Rat   807 FDPGTSIRYSCDPGYFLVGEDTIHCTSEGKWTPIPPQCKVAECKPVGPHVFERPQNHF-IRPAIN 870

  Fly   601 STASSGIGGSSTS---TVGTYPSLSPTQVEINGESESEEEINVPPVP 644
            |:...|...|.::   ..||.|..    :||    ...:||..||.|
  Rat   871 SSCDEGFQISESAYQLCQGTIPWF----IEI----RLCKEITCPPPP 909

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9095	NP_001096984.1	CCP	37..93	CDD:153056	18/58 (31%)
		FTP	94..242	CDD:128870	39/217 (18%)
		CLECT	256..375	CDD:214480	37/198 (19%)
		Sushi	381..435	CDD:278512	18/57 (32%)
		CCP	440..496	CDD:153056	19/132 (14%)
		CCP	500..556	CDD:153056	16/77 (21%)
Cr2	XP_008768069.1	PHA02927	10..274	CDD:222943	45/203 (22%)
		CCP	34..78	CDD:214478
		CCP	83..140	CDD:214478	18/57 (32%)
		CCP	145..212	CDD:153056	15/74 (20%)
		CCP	217..272	CDD:153056	8/54 (15%)
		CCP	276..333	CDD:153056	9/58 (16%)
		Sushi	337..395	CDD:278512	15/63 (24%)
		CCP	400..460	CDD:153056	6/59 (10%)
		CCP	468..525	CDD:153056	17/73 (23%)
		CCP	532..589	CDD:153056	18/58 (31%)
		CCP	593..650	CDD:153056	15/61 (25%)
		CCP	654..721	CDD:153056	4/66 (6%)
		CCP	729..785	CDD:153056	15/55 (27%)
		CCP	788..845	CDD:153056	6/56 (11%)
		CCP	905..972	CDD:153056	3/5 (60%)
		CCP	980..1036	CDD:153056
		PHA02927	1088..1341	CDD:222943
		CCP	1096..1152	CDD:153056
		CCP	1161..1217	CDD:153056
		CCP	1224..1281	CDD:153056
		CCP	1285..1342	CDD:153056
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100