DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment RpL37-1 and Kcnq4

DIOPT Version :10

Sequence 1:	NP_573005.1	Gene:	RpL37-1 / 32446	FlyBaseID:	FBgn0030616	Length:	93	Species:	Drosophila melanogaster
Sequence 2:	NP_001074611.1	Gene:	Kcnq4 / 60613	MGIID:	1926803	Length:	696	Species:	Mus musculus

Alignment Length:	28	Identity:	10/28 - (35%)
Similarity:	12/28 - (42%)	Gaps:	9/28 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CGRSSYHIQKSTCAQCGYPAAKLRSYNW 49
            ||.     |:|:.||..|    .|..||
Mouse    69 CGG-----QRSSAAQKRY----RRLQNW 87

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL37-1	NP_573005.1	PTZ00073	1..91	CDD:240257	10/28 (36%)
Kcnq4	NP_001074611.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Ion_trans	99..331	CDD:459842
		Interaction with CALM. /evidence=ECO:0000250\|UniProtKB:P56696	343..352
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	445..484
		KCNQ_channel	469..648	CDD:460954
		Interaction with CALM. /evidence=ECO:0000250\|UniProtKB:P51787	536..550
		C-terminal assembly domain (tetramerization). /evidence=ECO:0000250\|UniProtKB:P56696	547..651
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	589..609
Blue background indicates that the domain is not in the aligned region.

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