DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL37a and Kcnq5

DIOPT Version :9

Sequence 1:	NP_001259561.1	Gene:	RpL37a / 32446	FlyBaseID:	FBgn0030616	Length:	93	Species:	Drosophila melanogaster
Sequence 2:	NP_001153611.1	Gene:	Kcnq5 / 226922	MGIID:	1924937	Length:	952	Species:	Mus musculus

Alignment Length:	97	Identity:	21/97 - (21%)
Similarity:	32/97 - (32%)	Gaps:	15/97 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FGKRHNKTHTLCRRCGRSSYHIQKS--------------TCAQCGYPAAKLRSYNWSVKAKRRKT 58
            |.||.|....|.:...||....:||              ||:.......:..|..:....::...
Mouse   364 FEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFCSNKQKFFR 428

  Fly    59 TGTGRMQHLKV-VRRRFRNGFREGTQAKPKKA 89
            ..|.|.|..|: .:.|.|.....|...|.::|
Mouse   429 VYTSRKQSQKLSFKERVRMASPRGQSIKSRQA 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL37a	NP_001259561.1	PTZ00073	1..91	CDD:240257	21/97 (22%)
Kcnq5	NP_001153611.1	Ion_trans	161..359	CDD:278921
		Ion_trans_2	275..349	CDD:285168
		Selectivity filter. /evidence=ECO:0000250	312..317
		KCNQ_channel	473..660	CDD:281513
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	597..617
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	897..952
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900