Protein Alignment RpL37a and Kcnd2

DIOPT Version :9

• Sequence 1: NP_001259561.1
• Gene: RpL37a / 32446
• FlyBaseID: FBgn0030616
• Length: 93
• Species: Drosophila melanogaster
• Sequence 2: NP_062671.1
• Gene: Kcnd2 / 16508
• MGIID: 102663
• Length: 630
• Species: Mus musculus
• Alignment Length: 15
• Identity: 6/15 - (40%)
• Similarity: 9/15 - (60%)
• Gaps: 0/15 - (0%)

  Fly    22 CGRSSYHIQKSTCAQ 36
            ||.|..||::..|.:
Mouse   209 CGSSPGHIKELPCGE 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpL37a	NP_001259561.1	PTZ00073	1..91	CDD:240257	6/15 (40%)
Kcnd2	NP_062671.1	Interaction with KCNIP1, KCNIP2, and other family members. /evidence=ECO:0000250|UniProtKB:Q63881	2..20
		Shal-type	3..28	CDD:288455
		BTB	43..140	CDD:197585
		BTB_2	43..132	CDD:280393
		Interaction with KCNIP1. /evidence=ECO:0000250|UniProtKB:Q63881	71..90
		Ion_trans	216..415	CDD:278921	2/8 (25%)
		S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142	308..321
		Ion_trans_2	331..411	CDD:285168
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	370..375
		DUF3399	445..546	CDD:288712
		Important for normal channel activation and inactivation, for interaction with KCNIP2, and probably other family members as well. /evidence=ECO:0000250|UniProtKB:Q63881	474..630
		Required for dendritic targeting. /evidence=ECO:0000250|UniProtKB:Q63881	474..489
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	600..623
		PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q63881	627..630

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900