DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL37a and Kcna3

DIOPT Version :9

Sequence 1:	NP_001259561.1	Gene:	RpL37a / 32446	FlyBaseID:	FBgn0030616	Length:	93	Species:	Drosophila melanogaster
Sequence 2:	NP_032444.2	Gene:	Kcna3 / 16491	MGIID:	96660	Length:	528	Species:	Mus musculus

Alignment Length:	104	Identity:	23/104 - (22%)
Similarity:	31/104 - (29%)	Gaps:	26/104 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKSTCAQCGYPAAKL------RSYNWSVKAKRRKTT 59
            :|..|..:|..|..|         ....|..|.||..|.....|      .::|:..   .|:|.
Mouse   393 VTMTTVGYGDMHPVT---------IGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY---HRETE 445

  Fly    60 G--------TGRMQHLKVVRRRFRNGFREGTQAKPKKAV 90
            |        .|..|||.......|......|.:|.:..|
Mouse   446 GEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMV 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL37a	NP_001259561.1	PTZ00073	1..91	CDD:240257	23/104 (22%)
Kcna3	NP_032444.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		BTB	59..153	CDD:197585
		BTB_2	59..150	CDD:280393
		Ion_trans	243..443	CDD:278921	12/61 (20%)
		Ion_trans_2	357..434	CDD:285168	11/49 (22%)
		Selectivity filter. /evidence=ECO:0000250	397..402		1/4 (25%)
		PDZ-binding. /evidence=ECO:0000250	526..528
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900