DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL37a and kcnc2

DIOPT Version :9

Sequence 1:	NP_001259561.1	Gene:	RpL37a / 32446	FlyBaseID:	FBgn0030616	Length:	93	Species:	Drosophila melanogaster
Sequence 2:	NP_001082998.2	Gene:	kcnc2 / 100037377	ZFINID:	ZDB-GENE-070410-118	Length:	597	Species:	Danio rerio

Alignment Length:	72	Identity:	16/72 - (22%)
Similarity:	25/72 - (34%)	Gaps:	20/72 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TKGTSSFG-----KRHNKTHTLCRRCGRSSYHIQKSTCAQCG-------YPAAKLRSYNWSVKAK 54
            |:|....|     :||        |.|.:..|:.....|.|.       .|..::...:.||:.:
Zfish   478 TQGELCIGQSRGLERH--------RSGETLVHLHAVLSADCSAGSDISMSPEERMPMRHSSVREQ 534

  Fly    55 RRKTTGT 61
            ...|.||
Zfish   535 DHHTEGT 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL37a	NP_001259561.1	PTZ00073	1..91	CDD:240257	16/72 (22%)
kcnc2	NP_001082998.2	amino terminal assembly domain	1..185
		BTB	10..123	CDD:197585
		BTB_2	10..115	CDD:280393
		S1-S6 membrane domain	186..504		8/33 (24%)
		Ion_trans	235..442	CDD:278921
		Ion_trans_2	<385..432	CDD:285168
		post S6 proximal carboxyl terminal domain	505..560		8/37 (22%)
		distal carboxyl terminus	561..597
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900