Protein Alignment Cyp4s3 and DIT2

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 505
• Identity: 114/505 - (22%)
• Similarity: 217/505 - (42%)
• Gaps: 69/505 - (13%)

  Fly     3 TLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGELIANVKKGEILN-WLKELREKHGPV 66
            ||:.|||.:....|.: ||  |...:..:...||      :|..:.:.|:.: :::|..||:|.|
Yeast    14 TLSYVAFAIIVPPLNF-PK--NIPTIPFYVVFLP------VIFPIDQTELYDLYIRESMEKYGAV 69

  Fly    67 FRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRN-----YELLEPWLGKGLLTNGGESWHRRRKL 126
             :.:||....::.:..|.:.|:..:.....||.|     |..|..:.|..:::..|..|...|..
Yeast    70 -KFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGAVWRNYRNA 133

  Fly   127 LTPGFHFRILSEFKE-PMEENCRILVRRLRTK-ANGE-SFDIYPYITLFALDAICETAMGIKKHA 188
            :|.|     |..|.: |:.:|.:||...::.: ..|: |..:.|.....|||.|.:.|:|....|
Yeast   134 VTNG-----LQHFDDAPIFKNAKILCTLIKNRLLEGQTSIPMGPLSQRMALDNISQVALGFDFGA 193

  Fly   189 QLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQL 253
            .....:.:.:.:..|.:.:....|..:..|:|.     |...|:.|.|.:......:::..:::|
Yeast   194 LTHEKNAFHEHLIRIKKQIFHPFFLTFPFLDVL-----PIPSRKKAFKDVVSFRELLVKRVQDEL 253

  Fly   254 IQERNEWKPE----AEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSS 314
            :   |.:|.|    |..|.:.|... ..:|...||              :.:...:..||:....
Yeast   254 V---NNYKFEQTTFAASDLIRAHNN-EIIDYKQLT--------------DNIVIILVAGHENPQL 300

  Fly   315 AIAFALSLLSK-NPDVQQRAFEEASEL-EGREKESMPYLEAVIKETLRIYPSV-PFFSRKVLEDL 376
            ....:|.||:| :.:.|::..:|.:.: :.:....:|.|.|.:.|.:|:||.: ...:|...:..
Yeast   301 LFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGLADLPLLNAFLFEVVRMYPPLSTIINRCTTKTC 365

  Fly   377 EVG-KLTVPKGASISCLIYMLHRDPKNFP------DPERFDPDRFLVNEK---QMHPFAFAAFSA 431
            ::| ::.:|||..:....:....|||.:.      .|||:..|...:.:.   ..:..|...|..
Yeast   366 KLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHG 430

  Fly   432 GPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPK-----PLAELVTK 476
            |.|.|:|:|.|:.|::.|||.:|:.:|:..|.:.:.|     ||..|..|
Yeast   431 GRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLK 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	98/443 (22%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	99/445 (22%)