DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and CYP94D1

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_174713.1	Gene:	CYP94D1 / 840356	AraportID:	AT1G34540	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	135/537 - (25%)
Similarity:	249/537 - (46%)	Gaps:	92/537 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPG----PTIGE---LIANVKKGEILNWLKELRE 61
            :||:.|:    ||...|..:.|:...:.:.:..|    |.:|.   |:.|  :...|:|..|...
plant     1 MALLIFI----FLLCFPISIFFIFFTKKSSSEFGFKSYPIVGSFPGLVNN--RHRFLDWTVETLS 59

  Fly    62 K---HGPVFRIWFGKDLMVMFTDPEDIKQLLGNN-QLLTKSRNY-ELLEPWLGKGLLTNGGESWH 121
            :   ...:|| ..||..::|..:|.:::.:|... :...|.:.: .:||.:||.|:..:.|:.|.
plant    60 RCPTQTAIFR-RPGKQQLIMTANPSNVEYMLKTKFESFPKGQQFTSVLEDFLGHGIFNSDGDMWW 123

  Fly   122 RRRKLLTPGFHFRILSEF---KEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMG 183
            ::||..:..|..:.|.:|   ...:|.|.|::...:.....|:..|:...:..||.|.||:.|..
plant   124 KQRKTASYEFSTKSLRDFVMSNVTVEINTRLVPVLVEAATTGKLIDLQDILERFAFDNICKLAFN 188

  Fly   184 IKKHAQLQSDS----EYVQAVQSICRVMHKQSFSF----W---QRLNVFFKHTKPGKER--EAAL 235
            : ..|.|..|.    .:::|.::...::.::..|.    |   ::||:       |.||  ..::
plant   189 V-DCACLGHDGAVGVNFMRAFETAATIISQRFRSVASCAWRIKKKLNI-------GSERVLRESI 245

  Fly   236 KVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDI-RE 299
            ..:|...:.::|.|.:|       .:....::|             ||::.....|::..:| |:
plant   246 ATVHKFADEIVRNRIDQ-------GRSSDHKED-------------LLSRFISKEEMNSPEILRD 290

  Fly   300 EVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGR------------EKESMPYLE 352
            .|.:|:..|.||||||:::...|||.:|:|:.:..:|.:.:..|            ..:.|.||.
plant   291 IVISFILAGRDTTSSALSWFFWLLSMHPEVEDKILQELNSIRARTGKRIGEVYGFEHLKMMNYLH 355

  Fly   353 AVIKETLRIYPSVPFFSRKVLED--LEVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRF 414
            |.|.|:||:||.||...:...||  |..|.. |.||.:|:..|:.:.|....: .|.:||||:|:
plant   356 AAITESLRLYPPVPVDIKSCAEDNVLPDGTF-VGKGWAITYNIFAMGRMESIWGKDCDRFDPERW 419

  Fly   415 LVNE-----KQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF---LPDKDHQPKPLA 471
             ::|     :...|..|.||.||||.|:|:..|.:::|:.:|.:|.  ||   :|.|: :|:.|.
plant   420 -IDETNGCFRGEDPSKFPAFHAGPRMCVGKDMAYIQMKSIVAAVLE--RFVVEVPGKE-RPEILL 480

  Fly   472 ELVTKSGNGIRLRILPR 488
            .:..:...|:..|:..|
plant   481 SMTLRIKGGLFARVQER 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	124/485 (26%)
CYP94D1	NP_174713.1	CYP86A	64..490	CDD:410687	117/459 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920