DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and CYP715A1

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_200053.2	Gene:	CYP715A1 / 835316	AraportID:	AT5G52400	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	134/545 - (24%)
Similarity:	219/545 - (40%)	Gaps:	103/545 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LWAAFLRYLPKI--LNFLRL--------QRFAKTL-------PGPT--IGEL------------I 44
            :|..|.:....:  |.||:|        .|..|.|       |.|:  .|.|            :
plant     9 VWYIFFKVFVVVICLMFLKLFLRCWIWPVRAQKKLRGNGFVGPAPSFPFGNLNDMKKLKMASVVV 73

  Fly    45 ANVKKGEILN-------------WLKELREKHGPVFRIWFGKDLMVMFTDPEDI----KQLLGNN 92
            .|.|...|:|             |    ::::|.||..|.|.:..|...|||.:    |.:||.:
plant    74 DNSKSSTIINHDIHSIALPHFARW----QQEYGKVFVYWLGIEPFVYVADPEFLSVMSKGVLGKS 134

  Fly    93 ----QLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRR 153
                .:..|.|     ||..|.||:...|:.|.|.|.::||.|....|......|.|:...::.|
plant   135 WGKPNVFKKDR-----EPMFGTGLVMVEGDDWTRHRHIITPAFAPLNLKVMTNMMVESVSNMLDR 194

  Fly   154 --LRTKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQ 216
              ::..:....||:...|...|.:.|.:|:.|:       :.....|.:::: |.:....|:..:
plant   195 WGIQINSGNPEFDMESEIIGTAGEIIAKTSFGV-------TGENGTQVLKNL-RAVQFALFNSNR 251

  Fly   217 RLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDML 281
            .:.|.|.:....|:...|..:.|:....::....::.|.       .||.||.|..    .|.||
plant   252 YVGVPFSNILSYKQTVKAKGLGHEIDGLLLSFINKRKIS-------LAEGDDQGHD----LLGML 305

  Fly   282 LLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREK- 345
            |....:|  ..:..::.:|..||.|.||:||:.|:.:...||:.:|:.|....||..|:.|..|
plant   306 LKADQKG--NFTAKELVDECKTFFFAGHETTALALTWTFMLLAIHPEWQDTIREEIREVIGDSKI 368

  Fly   346 -----ESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPD 405
                 ..:..:..|:.|.||:||..|...|:...|:||....:|.|.:|...:..:|.|.:.:.|
plant   369 EYNKLAGLKKMSWVMNEVLRLYPPAPNAQRQARNDIEVNGRVIPNGTNIWIDVVAMHHDVELWGD 433

  Fly   406 ------PERFDPDRF--LVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPD 462
                  |||||.:..  ..|:....||.|     |.|.|||:....:|.|..|:::|..:.....
plant   434 DVNEFKPERFDGNLHGGCKNKMGYMPFGF-----GGRMCIGRNLTTMEYKIVLSLVLSRFEISVS 493

  Fly   463 KDHQPKPLAELVTKSGNGIRLRILP 487
            ..::..|...|..:.|.|:.|.|.|
plant   494 PGYRHSPTYMLSLRPGYGLPLIIRP 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	119/491 (24%)
CYP715A1	NP_200053.2	p450	16..519	CDD:299894	132/538 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870