DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and AT5G08250

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001330676.1	Gene:	AT5G08250 / 830721	AraportID:	AT5G08250	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	126/527 - (23%)
Similarity:	231/527 - (43%)	Gaps:	75/527 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGEL--IANVKKGEILNWLKELREKHGPVFRI 69
            :||.::|.        ::.||.::.......|.:|.|  :.:..:..|..||.::.......||.
plant    44 IAFFVFAT--------IHSLRQKKHQGMPVWPLVGMLPSLISAVRSNIYEWLSDVLISQNGTFRF 100

  Fly    70 ---WFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNY--ELLEPWLGKGLLTNGGESWHRRRKLLTP 129
               ||.....|:..||.:::.||.....:....:|  |.::..||.|:......:|.|:||..:.
plant   101 RGPWFSTLNCVVTCDPRNVEHLLKTRFSIYPKGSYFRETMQDLLGDGIFNTDDGTWQRQRKAASV 165

  Fly   130 GFHFRILSEFKEPMEENCRILV--RRLRTKANGESFDIYPYITLFALDAICETAMGI------KK 186
            .||   .::|::...::...||  |.|.........|:...:.....|.:|..|.|:      .|
plant   166 EFH---SAKFRQLTSQSLHELVHNRLLPVLETSGKIDLQDILLRLTFDNVCMIAFGVDPGCLSPK 227

  Fly   187 HAQLQSDSEYVQAVQ-SICR-VMHKQSFSFWQRLNVFFKHTKPGKER--EAALKVLHDETNRVIR 247
            ..::.....:..|.: ::.| ||.|..:...:.||:       |.|:  :.::..:.|....|||
plant   228 LPEIPFAKAFEDATEATVVRFVMPKFVWKLMRSLNL-------GTEKKLKESINGVDDFAEEVIR 285

  Fly   248 LRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTT 312
            .|::::..|..            ..:|...|.:.:..:.|.|.:.||..:|:....|:..|.||:
plant   286 TRKKEMSLETE------------IAKRPDLLTIFMGLRDENGQKFSDKFLRDICVNFILAGRDTS 338

  Fly   313 SSAIAFALSLLSKNPDVQQRAFEEASE-LEGR-------------------EKESMPYLEAVIKE 357
            |.|:::...|:.|||:|:::......: ||.|                   |.:.|.||:|.:.|
plant   339 SVALSWFFWLIEKNPEVEEKIMMGICKILEQRVDHGDTKKNMEYEPVFRPEEIKKMDYLQAALSE 403

  Fly   358 TLRIYPSVPFFSRKVLE-DLEVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFLVNEKQ 420
            |||:|||||...::||| |:......:.||..:...||.:.|....: .|...|.|:|:|.:.:.
plant   404 TLRLYPSVPVDHKEVLEDDVFPDGTKLKKGEKVIYAIYAMGRMETIWGKDCREFKPERWLRDGRY 468

  Fly   421 M--HPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF-LPDK-DHQPKPLAELVTKSGNGI 481
            |  ..:.|.||:.|||.|:|:.||..:::...|.::..|:. :.|| .|:.:|...|.....:|:
plant   469 MSESAYKFTAFNGGPRLCLGKDFAYYQMRYVAAAIIYRYKVRVDDKGGHKVEPKMALTMYMKHGL 533

  Fly   482 RLRILPR 488
            ::.::.|
plant   534 KVNMVKR 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	117/478 (24%)
AT5G08250	NP_001330676.1	CYP86A	98..533	CDD:410687	113/456 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920