DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4s3 and CPD

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_196188.1	Gene:	CPD / 830453	AraportID:	AT5G05690	Length:	472	Species:	Arabidopsis thaliana

Alignment Length:	502	Identity:	125/502 - (24%)
Similarity:	198/502 - (39%)	Gaps:	113/502 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 WAAFLRYLPKI----LNFLRLQRFAK--TLPG----PTIGE---LIANVKKGEILNWLKELREKH 63
            :.|||..|..|    |..||..|:.:  ..||    |.|||   ||...|......::.|...::
plant     3 FTAFLLLLSSIAAGFLLLLRRTRYRRMGLPPGSLGLPLIGETFQLIGAYKTENPEPFIDERVARY 67

  Fly    64 GPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEP-----WLGKG--LLTNGGESWH 121
            |.||......:..:...|||..:.:|.|     :.:.:|...|     .|||.  ||..|  |.|
plant    68 GSVFMTHLFGEPTIFSADPETNRFVLQN-----EGKLFECSYPASICNLLGKHSLLLMKG--SLH 125

  Fly   122 RRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMGIKK 186
            :|...||  ..|...|..|:.:..:...|||                   |.||:.....:
plant   126 KRMHSLT--MSFANSSIIKDHLMLDIDRLVR-------------------FNLDSWSSRVL---- 165

  Fly   187 HAQLQSDSEYVQAVQSICRVMHKQSFSF----WQR---------LNVFFKHTKP------GKERE 232
               |..:::.:....::     ||..||    |..         :..||....|      .|..:
plant   166 ---LMEEAKKITFELTV-----KQLMSFDPGEWSESLRKEYLLVIEGFFSLPLPLFSTTYRKAIQ 222

  Fly   233 AALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDML--LLTQMEGGAELSDT 295
            |..||.  |...|:.::|.             |:::.||:|:   .|||  ||...:|   .||.
plant   223 ARRKVA--EALTVVVMKRR-------------EEEEEGAERK---KDMLAALLAADDG---FSDE 266

  Fly   296 DIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEE----------ASELEGREKESMPY 350
            :|.:.:...:..|::|||:.:..|:..|::.|....:..||          :..||..:.:|||:
plant   267 EIVDFLVALLVAGYETTSTIMTLAVKFLTETPLALAQLKEEHEKIRAMKSDSYSLEWSDYKSMPF 331

  Fly   351 LEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFL 415
            .:.|:.||||:...:....|:.:.|:|:....:|||..:......:|.||.:|.|...|:|.|:.
plant   332 TQCVVNETLRVANIIGGVFRRAMTDVEIKGYKIPKGWKVFSSFRAVHLDPNHFKDARTFNPWRWQ 396

  Fly   416 VNEKQMHPF-AFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLP 461
            .|.....|. .|..|..|||.|.|.:.|.:.|...|..|:..:.::|
plant   397 SNSVTTGPSNVFTPFGGGPRLCPGYELARVALSVFLHRLVTGFSWVP 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	116/473 (25%)
CPD	NP_196188.1	p450	1..472	CDD:386267	125/502 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920