DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and CYP96A11

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001328516.1	Gene:	CYP96A11 / 830104	AraportID:	AT4G39500	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	123/538 - (22%)
Similarity:	221/538 - (41%)	Gaps:	91/538 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGEL-IANVKKGEILNWLKELREKHGP 65
            :::|:..|::    |.||.|...:  ..||.:.  .|.:|.| ...|....|.:::.|:.|....
plant    19 ASVAIFCFLI----LHYLFKTTTY--NGRFPRN--WPVLGMLPCLLVVLHRIYDYIVEILEISDL 75

  Fly    66 VFRI---WF-GKDLMVMFTDPEDIKQLLGNN-QLLTKSRNYELLEPWLGKGLLTNGGESWHRRRK 125
            .|..   || |.|.: :..||.:|..::.:| ....|..:::.:....|.|::|...|.|...||
plant    76 TFSFKGPWFAGMDTL-LTVDPANIHHMMNSNFSNYIKGSDFKEVFDVFGDGIITTDSELWKNLRK 139

  Fly   126 LLTPGFHFRILSEF-----KEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMGIK 185
            ......|.:....|     :..:::....|:.....:  |.:.|:...:..|..|.|.....|
plant   140 SYQEMLHHQAFQSFSLSTTRSKLKDGLVPLLNHFAEE--GTTVDLQDVLGRFTFDTILILITG-- 200

  Fly   186 KHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNV-----FFKHTKP------------GKERE- 232
                  ||.      :|:...||:...:  :.|:|     ||:|.||            |.|::
plant   201 ------SDP------RSLSIEMHEDELA--KALDVVGEGIFFRHVKPKFLWKLQNWMGFGHEKKM 251

  Fly   233 ---------AALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEG 288
                     ...|.:.|:...:||.:|   ..:.:..:||   |.:.:..:|......||...:
plant   252 IEANATFDRVCAKYISDKRGEIIRSQR---FSDISYGEPE---DLLSSFMKLDTTKYNLLNPSD- 309

  Fly   289 GAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEE------ASELEGREK-E 346
                 |..:|:.:..|:..|.|||:||:.:...|||:|..|..:..:|      :....|:|. :
plant   310 -----DKFLRDTILAFILAGRDTTASALTWFFWLLSENAQVVSKIRQEIINTNPSKNGNGQENLD 369

  Fly   347 SMPYLEAVIKETLRIYPSVPFFSRK--VLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPE-R 408
            .:.||...:.|.:|:||.|. |.||  :..|:......|...:.|...:|.|.|....:.|.. .
plant   370 KLVYLHGALCEAMRLYPPVS-FGRKSPIKSDVLPSGHKVQANSKIIICLYALGRMRAVWGDDALE 433

  Fly   409 FDPDRFLVNEKQMH---PFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPL 470
            |.|:|::.::..:.   .|.|.:|::|||.|:|:..||.::|.....:|.:|.....|..:.||:
plant   434 FKPERWVSDKGSLRHEPSFKFLSFNSGPRTCLGKHLAMTQMKMVAVEILHNYEIKVIKGQKIKPV 498

  Fly   471 AELVTKSGNGIRLRILPR 488
            ...:....:|:|:.|..|
plant   499 LGFILSMKHGLRITITKR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	109/484 (23%)
CYP96A11	NP_001328516.1	p450	10..516	CDD:386267	122/536 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920