DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4s3 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	146/545 - (26%)
Similarity:	227/545 - (41%)	Gaps:	99/545 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TLALVAFVL-------WAAFLRYLPKILNFLRLQRFAKT-LPGPTIGELIANVKKGEILNWLKEL 59
            |:.|:.||:       |...||  |.:|:    :||.|. :.||....|..|:  .||....||.
plant    11 TIVLLLFVVSKIWKACWILLLR--PLMLS----KRFKKQGISGPKYKILYGNL--SEIKKMKKEA 67

  Fly    60 -----------------------REKHGPVFRIWFGKDLMVMFTDPEDIKQLL----GNNQLLTK 97
                                   ..::|..|..|.|....:..::.|..||:|    |...:..|
plant    68 DLCVLDPNSNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKFGFTIIPVK 132

  Fly    98 SRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEE-NCRILVRRLRTKANGE 161
            .....:|   .||||....|:.|.|.|::|.|.|....|....:||.: ..||.....:.:.|||
plant   133 RPEVFIL---FGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLRIFEEWRKQRRNGE 194

  Fly   162 ---SFDIYPYITLFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHK-QSFSFWQRLNVFF 222
               ..:|.........|.|..||.|          |.|.:.:: :||...: :.:......|||.
plant   195 VLIKIEISKEFHKLTADIIATTAFG----------SSYAEGIE-LCRSQTELEKYYISSLTNVFI 248

  Fly   223 KHTKPGKE---REAALKV--LHDETNRVIRLRREQLIQER--NEWKPEAEQDDVGAKRRLAFLDM 280
                ||.:   ....||:  ||.:....|:    ::|..|  ::.|.....||:        |.:
plant   249 ----PGTQYLPTPTNLKLWELHKKVKNSIK----RIIDSRLKSKCKTYGYGDDL--------LGV 297

  Fly   281 LLLTQMEGGAE--LSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGR 343
            :|........|  :...:|.||...|.:.|..|||..:.:...|||.:...|::..||.....|:
plant   298 MLTAAKSNEYERKMRMDEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLREEVFNECGK 362

  Fly   344 EK-------ESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPK 401
            :|       ..:..:..|:.|:||:|..|...||:..:|::||.|.:|||.||...:..:|||..
plant   363 DKIPDTDTFSKLKLMNMVLMESLRLYGPVIKISREATQDMKVGHLEIPKGTSIIIPLLKMHRDKA 427

  Fly   402 NF-PDPERFDPDRFL--VNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYR--FLP 461
            .: .|.|:|:|.||.  :::..:||.|...||.|||.||.:.|||:|.||.|.|:|:.::  ..|
plant   428 IWGEDAEQFNPLRFENGISQATIHPNALLPFSIGPRACIAKNFAMVEAKTVLTMILQQFQLSLSP 492

  Fly   462 DKDHQPKPLAELVTKSGNGIRLRIL 486
            :..|.|....:|..:.|..:.|..|
plant   493 EYKHTPVDHFDLFPQYGLPVMLHPL 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	130/486 (27%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	145/543 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H73900
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860