DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and LUT1

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	480	Identity:	126/480 - (26%)
Similarity:	214/480 - (44%)	Gaps:	56/480 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 IANVKKGEILN------------WLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLT 96
            |||.|..::.:            |:.|    :||::|:..|....|:.:||...|.:|.|.....
plant    81 IANAKLDDVADLLGGALFLPLYKWMNE----YGPIYRLAAGPRNFVIVSDPAIAKHVLRNYPKYA 141

  Fly    97 KSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENC-RILVRRLRTKA-N 159
            |....|:.|...|.|.....|..|..||:.:.|..|.|.||...|.:...| ..||.:|:..| :
plant   142 KGLVAEVSEFLFGSGFAIAEGPLWTARRRAVVPSLHRRYLSVIVERVFCKCAERLVEKLQPYAED 206

  Fly   160 GESFDIYPYITLFALDAICETAMGIK----KHAQLQSDSEYVQAVQSICRVMHKQS---FSFWQR 217
            |.:.::....:...||.|     |:.    ....|.:||..::||.:..:....:|   ..:| :
plant   207 GSAVNMEAKFSQMTLDVI-----GLSLFNYNFDSLTTDSPVIEAVYTALKEAELRSTDLLPYW-K 265

  Fly   218 LNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLL 282
            ::...|......:.|.|:.::.:....:|...:|.:.:|......|...:|...    :.|..||
plant   266 IDALCKIVPRQVKAEKAVTLIRETVEDLIAKCKEIVEREGERINDEEYVNDADP----SILRFLL 326

  Fly   283 LTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASE-LEGR--- 343
            .::    .|:|...:|:::.:.:..||:||.|.:.:.|.|||||....::|.||... ||||
plant   327 ASR----EEVSSVQLRDDLLSMLVAGHETTGSVLTWTLYLLSKNSSALRKAQEEVDRVLEGRNPA 387

  Fly   344 --EKESMPYLEAVIKETLRIYPSVPFFSRKV-LEDLEVGKLTVPKGASISCLIYMLHRDPKNFPD 405
              :.:.:.|:...|.|::|:||..|...|:. :.|:..|...|..|..|...:|.:||..:.:..
plant   388 FEDIKELKYITRCINESMRLYPHPPVLIRRAQVPDILPGNYKVNTGQDIMISVYNIHRSSEVWEK 452

  Fly   406 -----PERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLR--SYRFLPDK 463
                 |||||.|..:.||... .|.|..||.|||.|:|.:||::|...:||:.|:  :...:||:
plant   453 AEEFLPERFDIDGAIPNETNT-DFKFIPFSGGPRKCVGDQFALMEAIVALAVFLQRLNVELVPDQ 516

  Fly   464 DHQPKPLAELVTKSGNGIRLRILPR 488
            .......|.:.|.  ||:.:::..|
plant   517 TISMTTGATIHTT--NGLYMKVSQR 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	121/459 (26%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	125/478 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920