DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and CYP72A14

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_188086.1	Gene:	CYP72A14 / 820696	AraportID:	AT3G14680	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	142/537 - (26%)
Similarity:	231/537 - (43%)	Gaps:	88/537 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TLALVAFVLWA----AFLRYLPKIL-NFLRLQRFAKTLPGPTIGELIANVKKGEILNWLKELREK 62
            :||:|....|.    .::.:.||:| ..||.|..:.|...|.||:.    ||  :::...|...|
plant    11 SLAVVVVSWWVWRTLKWVWFTPKMLERSLRRQGLSGTSYTPLIGDF----KK--MISMFIEATSK 69

  Fly    63 ----------------------HGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLE 105
                                  ||.....|||....:...|||.||::........|:..:. |.
plant    70 PIKPTDDITPRVMPHPLQMLKTHGRTNLTWFGPIPTITIMDPEQIKEVFNKVYDFQKAHTFP-LS 133

  Fly   106 PWLGKGLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILV----RRLRTKANGESFDIY 166
            ..||.||::..|:.|.:.|:::.|.||...:........|:|..||    :.:..|.:....|::
plant   134 KILGTGLVSYDGDKWAQHRRIINPAFHLEKIKNMVHVFHESCSELVGEWDKLVSDKGSSCEVDVW 198

  Fly   167 PYITLFALDAICETAMGI---KKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPG 228
            |.:|....|.|..||.|.   :.|...:..:|..|.|.        |:|..:......:..||..
plant   199 PGLTSMTADVISRTAFGSSYREGHRIFELQAELAQLVM--------QAFQKFFIPGYIYLPTKGN 255

  Fly   229 KEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLL---LTQMEGGA 290
            :..:.|.:.:.|....:|..|      ||.....||..:|:        |.:||   |.|.||..
plant   256 RRMKTAAREIQDILRGIINKR------ERARESGEAPSEDL--------LGILLESNLGQTEGNG 306

  Fly   291 ELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREK------ESMP 349
             :|..|:.||...|...|.:|||..:.:.:.|||::.|.|.||.||..::.|.::      ..:.
plant   307 -MSTEDMMEECKLFYLAGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGDKQPDTEGLNQLK 370

  Fly   350 YLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDR 413
            .:..::.|.||:||.|...:|.:.:::::|.||:|.|..||..:.::|||.:.: .|...|.|:|
plant   371 VMTMILYEVLRLYPPVVQLTRAIHKEMKLGDLTLPGGVQISLPVLLVHRDTELWGNDAGEFKPER 435

  Fly   414 F-------LVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLR--SYRFLPDKDHQPKP 469
            |       ..|:....|||:     |||.||||.|.:||.|.:::::|:  |:...|...|.|..
plant   436 FKDGLSKATKNQVSFFPFAW-----GPRICIGQNFTLLEAKMAMSLILQRFSFELSPSYVHAPYT 495

  Fly   470 LAELVTKSGNGIRLRIL 486
            :..|..:.|..:.|..|
plant   496 IITLYPQFGAHLMLHKL 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	127/481 (26%)
CYP72A14	NP_188086.1	p450	24..512	CDD:299894	137/522 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.860