DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and CYP96A5

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_179782.1	Gene:	CYP96A5 / 816727	AraportID:	AT2G21910	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	497	Identity:	117/497 - (23%)
Similarity:	208/497 - (41%)	Gaps:	74/497 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LPG-----PTIGELIANVKKGEILNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNN-Q 93
            |||     ..|.:.:|.:.  |:.|.....:   ||    ||....|::..||.:|:.:..:| .
plant    41 LPGVLVMLHRINDYVAEIL--EVSNLTFAFK---GP----WFSGMNMLITADPSNIQHVFSSNFS 96

  Fly    94 LLTKSRNYELLEPWLGKGLLTNGGESWHRRRK-----LLTPGFHFRILSEFKEPMEENCRI---L 150
            ...|...::.:..:||.|:.|...:.|...||     |...||....|...      .|:|   |
plant    97 NYDKGPEFKEMFDFLGNGIFTADSKLWEDMRKSALVVLSHQGFQSFSLRTI------TCKIKNGL 155

  Fly   151 VRRLRTKANGES-FDIYPYITLFALDAI------CETA-----MGIKKHAQLQSDSEYVQAVQSI 203
            |..|...|...: ||:.......|.|..      |:::     |...::|:...|:|.|...:
plant   156 VPVLDHFAEANTVFDLQDVFQRLAFDVTLTLVTGCDSSSLSIEMPKNEYAKAMDDAEEVVVYR-- 218

  Fly   204 CRVMHKQSFSFWQRLN-VFFKHTKPGKEREAALKVLHDET-NRVIRLRREQLIQERNEWKPEAEQ 266
                |.:....|:..| :.....|..||..||.    |.: .:.|..:||::|...:....||..
plant   219 ----HVKPVVLWKLQNWIGLGEEKKMKEANAAF----DRSCAKYISAKREEIISHHSNIGGEAHA 275

  Fly   267 DDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQ 331
            :|:     |:....|.:::.|......|..:::.:.:||..|.|..::.:.:...||||||:...
plant   276 EDL-----LSVYMNLDISKYELLNPNDDNFLKDIIKSFMLAGRDAIATTLTWFFWLLSKNPEAVT 335

  Fly   332 RAFEEAS--------ELEGREKESMPYLEAVIKETLRIYPSVPFFSRK--VLEDLEVGKLTVPKG 386
            :..:|.:        .|:..:...|.||...:.|:||:|..:| |.||  :.:|:......|.|.
plant   336 KIRQEINTNLPGSGMSLDADKLNKMVYLHGALCESLRLYAPIP-FERKTPIKQDVLPSGHMVDKN 399

  Fly   387 ASISCLIYMLHRDPKNF-PDPERFDPDRFLVNE----KQMHPFAFAAFSAGPRNCIGQKFAMLEL 446
            ..|...:|.|.|....: .|...|.|:|::...    |....|.|..|::|||||:|:..:.|::
plant   400 WKILFSVYALGRMRSVWGQDASEFKPERWISERNGGLKHEPSFKFFVFNSGPRNCLGKNLSFLQM 464

  Fly   447 KTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRILPR 488
            ||....::|:|.....:.|:.:|.:.::....:|:::.:..|
plant   465 KTVAVEIIRNYDIKVVEGHKIEPASSIILHMKHGLKVTVSKR 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	114/476 (24%)
CYP96A5	NP_179782.1	p450	1..506	CDD:299894	116/495 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920