Protein Alignment Cyp4s3 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001072655.1
• Gene: cyp26b1 / 780112
• XenbaseID: XB-GENE-991500
• Length: 511
• Species: Xenopus tropicalis
• Alignment Length: 538
• Identity: 135/538 - (25%)
• Similarity: 219/538 - (40%)
• Gaps: 101/538 - (18%)

  Fly     1 MSTLA--LVAFVLWAAFLRYLPKILNFLRLQRFAKT--------LPGPTIGELIANVKKGEILNW 55
            ::|||  ||:..|..|..:.|.::       |:|.|        :|..::|..:.    ||..:|
 Frog    12 LATLAACLVSVALLLAVSQQLWQL-------RWAATRDKSCKLPIPKGSMGFPLV----GETFHW 65

  Fly    56 L-------KELREKHGPVFRIWFGKDLMVMFTDPEDIKQ-LLGNNQLLTKS--RNYELLEPWLGK 110
            :       ...|||:|.||:.......::..|..|:::: |:|.:.|::..  |:..:|   ||.
 Frog    66 ILQGSDFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRML---LGP 127

  Fly   111 GLLTNG-GESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRT-KANGESFDIYPYITLFA 173
            ..|.|. |:....:||:.:..|....|..:...::   .::...||. .:|.||.::|.......
 Frog   128 NSLANSIGDIHRHKRKVFSKIFSHEALESYLPKIQ---LVIQDTLRVWSSNPESINVYCEAQKLT 189

  Fly   174 LDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRL--NVF-------FKHTKPG- 228
            ........:|.:     .||.|.            .|.|..:|:.  |||       |...:.|
 Frog   190 FRMAIRVLLGFR-----LSDEEL------------SQLFQVFQQFVENVFSLPVDVPFSGYRRGI 237

  Fly   229 KEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELS 293
            :.||..||.|            |:.|||:.:.....:..|.        ||:|:.:..|.|.||:
 Frog   238 RAREMLLKSL------------EKAIQEKLQNTQGKDYADA--------LDILIESGKEHGKELT 282

  Fly   294 DTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEE---------ASELEGREK---- 345
            ..::::.....:|..:.||:||....:..|.|:|.|.::..||         ....||..:
 Frog   283 MQELKDGTLELIFAAYATTASASTSLIMQLLKHPSVLEKLREELRGNSILHNGCVCEGALRVETI 347

  Fly   346 ESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFD 410
            .|:.||:.||||.||::..|....|.||:..|:....:|||.|:...|...|.....|.|.:.||
 Frog   348 SSLHYLDCVIKEILRLFSPVSGGYRTVLQTFELDGFQIPKGWSVLYSIRDTHDTAPVFKDVDVFD 412

  Fly   411 PDRFLVN--EKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAEL 473
            ||||..:  |.:...|.:..|..|.|||:|:..|.|.||.....|....||.......||.:...
 Frog   413 PDRFGQDRTEDKDGRFHYLPFGGGVRNCLGKHLAKLFLKVLAIELASMSRFELATRTFPKIMPVP 477

  Fly   474 VTKSGNGIRLRILPRDEN 491
            |....:.:::|....|.|
 Frog   478 VVHPADELKVRFFGLDSN 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	113/448 (25%)
cyp26b1	NP_001072655.1	CYP26B1	60..489	CDD:410730	119/471 (25%)