Protein Alignment Cyp4s3 and cyp46a1.3

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_073789299.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 499
• Species: Danio rerio
• Alignment Length: 526
• Identity: 143/526 - (27%)
• Similarity: 247/526 - (46%)
• Gaps: 92/526 - (17%)

  Fly     4 LALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGP-----TIGEL--IANVKKGE------ILNW 55
            |.::.::|.|.|:.:|...|...::......:|||     .:|.:  |..|.|.|      :|.|
Zfish     7 LYMLFYLLSAVFVVFLAYCLYIHQVHLKYDHIPGPPRDNFLLGHIPTINRVTKSERHMNDLLLIW 71

  Fly    56 LKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELL-----EPWLGKGLLT- 114
                .||:|||:|:.....:::....||..|.::.:.:.|.....|:.|     :.:||.||:|
Zfish    72 ----AEKYGPVYRLNSFHYVIINVHCPEATKTIMMSPKYLKDPFIYKRLFGLFGKRFLGYGLVTA 132

  Fly   115 NGGESWHRRRKLLTPGF---HFR-ILSEFKEPMEENCRILVRRLRTKA-NGESFDIYPYITLFAL 174
            ...:.|:|:|:::.|.|   :.| ::|.|.|..|.    |:.:|...| |.....::..:....|
Zfish   133 TDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSER----LMDKLEEMAINKTPAVMHDLVNCVTL 193

  Fly   175 DAICETAMGIKKHAQLQSDSEYVQAVQS------------ICRVMHKQSFSFWQRLNVFFKHTKP 227
            |.||:.|.|:..:...|:|:.:.||::.            .|:...|.    |
Zfish   194 DIICKVAFGVDLNLFKQTDNPFQQAIEQCLQGMVLDLRDPFCKFFPKN----W------------ 242

  Fly   228 GKEREAALKVLHDETNRVIRLRR--EQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGA 290
                    |.:.:.....:.||:  ||.||.|   |...|   :|.......|..:|.|..|  .
Zfish   243 --------KAIQETKGATVLLRKTGEQWIQNR---KTAVE---IGEDVPNDILTQILKTAKE--E 291

  Fly   291 ELSDTDIREEV----DTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREKE----- 346
            ::::|...|::    .||...|.:||::.::||:..|.::|::.:||..|..|:.|.:::
Zfish   292 KVNNTKDHEQMLDNFVTFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDEVLGTKRDISYED 356

  Fly   347 --SMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERF 409
              ...||..|:|||||:||:.|..:|.:.||:.:..:.:|.|.|:....|:..|..|:|.||.:|
Zfish   357 LGKFTYLSQVLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGISVIFSSYVAQRLEKHFKDPLKF 421

  Fly   410 DPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF--LPDKDHQPKPLAE 472
            ||:||.||..:.: :.:..||.|||:|:||.|:.:|.|..||.||:.:.|  :|.:..:.|.:..
Zfish   422 DPERFNVNAPKPY-YCYYPFSLGPRSCLGQVFSQMEAKVVLAKLLQRFEFSLVPGQSFEIKDIGT 485

  Fly   473 LVTKSG 478
            |..|||
Zfish   486 LRPKSG 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	125/453 (28%)
cyp46a1.3	XP_073789299.1	None