Protein Alignment Cyp4s3 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 520
• Identity: 133/520 - (25%)
• Similarity: 252/520 - (48%)
• Gaps: 76/520 - (14%)

  Fly     4 LALVAFVLWAAFLRYL----------PKILNFLRLQRFAKTLPGPTIGELIAN--VKKGEILNWL 56
            |.|:.|:|::.::.|:          |:...||.        ..||:..|:.|  :.....|.|:
 Frog    17 LILICFLLFSGYIHYIHMKYDHIPGPPRDSFFLG--------HSPTMLRLMKNNLLMYDHFLGWV 73

  Fly    57 KELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLE-----PWLGKGLLTNG 116
                :|:|||.||.....::::...||.:|:||.:.: .:|.:.|:::.     .::||||:|:.
 Frog    74 ----QKYGPVVRINGLHRVIILVVSPEAVKELLMSPK-YSKDKFYDVIANMFGVRFMGKGLVTDR 133

  Fly   117 G-ESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGE-SFDIYPYITLFALDAICE 179
            . :.||::|:::.|.|....|.....|..|....|:.:|..||:|: ...::..::...||.|.:
 Frog   134 DYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRLTLDVIGK 198

  Fly   180 TAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNR 244
            .|.|::.::.....:.:.:|:..:.:.:.:.     :...|.:...|.|..|:.      .|:.|
 Frog   199 VAFGMELNSLNDDLTPFPKAISLVMKGIVEM-----RNPMVRYSLAKRGFIRKV------QESIR 252

  Fly   245 VIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVD------- 302
            ::|...::.|:.|.:...:.|:..|.           :|||:..||.:     .||.|
 Frog   253 LLRQTGKECIERRQKQIQDGEEIPVD-----------ILTQILKGAAM-----EEECDPEILLDN 301

  Fly   303 --TFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREKE-------SMPYLEAVIKET 358
              ||...|.:||::.::|.:..|.:||::.::|..|..|:.|.:::       .:.||..|:|||
 Frog   302 FVTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIGSKRDIEYEDLGKLQYLSQVLKET 366

  Fly   359 LRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEKQMHP 423
            ||:||:.|..||.:.||:.:..:.||:..:|....|::.|..:.:.||..|:||||..:..:.:
 Frog   367 LRLYPTAPGTSRGLTEDMVIDGVKVPENVTIMLNSYIMGRMEQYYSDPLTFNPDRFSPDAPKPY- 430

  Fly   424 FAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRILPR 488
            :::..||.|||:||||.|:.:|.|..:|.||:.|.|...:....|.|.....:..:|:..|:.||
 Frog   431 YSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYEFELAEGQSFKILDTGTLRPLDGVICRLRPR 495

  Fly   489  488
             Frog   496  495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	119/458 (26%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	125/491 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910