Protein Alignment Cyp4s3 and cyp11a1.2

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_691817.1
• Gene: cyp11a1.2 / 563363
• ZFINID: ZDB-GENE-130911-1
• Length: 512
• Species: Danio rerio
• Alignment Length: 547
• Identity: 130/547 - (23%)
• Similarity: 214/547 - (39%)
• Gaps: 114/547 - (20%)

  Fly    12 WAAFLRYLPKILNFLRLQRFAKTLPG--PTIGELIANVK-----KGEILNWLKE---------LR 60
            |:...|....:.:...|.:...|..|  |.||...:.|:     .|:..|.||.         ||
Zfish     4 WSLSARLDQSVSSLKHLLQVIVTRSGRAPAIGLQDSTVRPFNEIPGQWRNSLKSVFAFAKMGGLR 68

  Fly    61 EKH----------GPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYE----LLEPWLG-- 109
            ..|          ||::|...|....|....|||.       .:|.|:..:.    .::.|..
Zfish    69 NIHRIMVHNFNTFGPIYREKVGFYESVNIIKPEDA-------AILFKAEGHYPKRLTIDAWTAYR 126

  Fly   110 ------KGLLTNGGESWHRRR-----KLLTPGFHFRILSEFKEPMEENCRILVRRL-----RTKA 158
                  .|:|...||.|...|     ::::|    ::...|...::|..:..|.|:     |:..
Zfish   127 DYRNRKYGVLLKDGEDWKSNRIILNKEVISP----KVQGNFVPLLDEVGQDFVARVNKKIERSGQ 187

  Fly   159 NGESFDIYPYITLFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFK 223
            |..:.|:...:..|||:::.....|.:....|    :|:.          ..|..|...:.:.||
Zfish   188 NQWTTDLSHELFKFALESVSAVLYGERLGLLL----DYID----------PDSQRFIDCITLMFK 238

  Fly   224 HTK------PGKEREAALKV----------LHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAK 272
            .|.      ||..|....|:          :.::.:|.|:....||  .:|   ||......|..
Zfish   239 TTSPMLYLPPGLLRPIRSKIWRNHVEAWDGIFNQADRCIQNIYRQL--RKN---PEGNGKYTGVL 298

  Fly   273 RRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEA 337
            ..|..||           :||..||:..|...|..|.|||:..:.:.|..|::|||:|:....|.
Zfish   299 ASLLMLD-----------KLSIEDIKASVTELMAGGVDTTAITLLWTLYELARNPDLQEEIRAEI 352

  Fly   338 SELEGREKESM-------PYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYM 395
            |......|..|       |.::..:|||||::|......|.:.||:.:.|..:|.|..:...:|.
Zfish   353 SAARIASKGDMVQMLKMIPLVKGTLKETLRLHPVAVSLQRYITEDIVIQKYHIPAGTLVQLGLYA 417

  Fly   396 LHRDPKNFPDPERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFL 460
            :.||.:.||:||::.|.|::  ..|.|.|...:|..|||.|:|::.|..|::..|..:|.::|..
Zfish   418 MGRDHQVFPNPEQYLPSRWV--NSQNHYFKSLSFGFGPRQCLGRRIAETEMQLFLIHMLENFRIE 480

  Fly   461 PDKDHQPKPLAELVTKSGNGIRLRILP 487
            ..:..:.|.:.||:......|.|.|.|
Zfish   481 KQRQMEVKSMFELILLPEKPIMLTIKP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	111/463 (24%)
cyp11a1.2	XP_691817.1	cytochrome_P450	78..501	CDD:477761	110/465 (24%)