Protein Alignment Cyp4s3 and cyp4v2a

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001071070.1
• Gene: cyp4v2a / 558851
• ZFINID: ZDB-GENE-061103-601
• Length: 513
• Species: Danio rerio
• Alignment Length: 494
• Identity: 198/494 - (40%)
• Similarity: 292/494 - (59%)
• Gaps: 33/494 - (6%)

  Fly    10 VLWAAFLRYLPKILNFLRLQRFAKTLPG-----PTIGELIANVKKG----EILNWLKELREKHGP 65
            |:..|::.| ..:.::|...:..|.:||     |.||..:.....|    :::.:..|.  ::.|
Zfish    19 VICFAYITY-QLLKSYLHKWKELKPIPGIGNTFPFIGNALQFKSNGDFFLQLVGYTTEF--QNSP 80

  Fly    66 VFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPG 130
            :.:||.|....::....|.::.:|.|...:.|:..|:.|.||||.||||:.|:.|.||||:|||.
Zfish    81 LLKIWIGPIPFLILFHAETVETVLNNPVHIDKAYAYQFLHPWLGTGLLTSTGDKWRRRRKMLTPT 145

  Fly   131 FHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDSE 195
            |||.||:||.|.|.|...:|:.:|..:|....|:.:.:|||.|||.|||||||.:.:||...|||
Zfish   146 FHFSILTEFLEVMNEQAEVLIEKLEKQAGKGPFNCFSHITLCALDIICETAMGKRIYAQSNYDSE 210

  Fly   196 YVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEW 260
            ||:.|..:..::.::....|...:..:.:...|:|...:||:||..|        |.:|.||.|:
Zfish   211 YVRTVYRMSDIITRRQRMPWYWPDFVYNYVGEGREHNRSLKILHSFT--------ESVINERAEY 267

  Fly   261 KPEAEQD---DVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSL 322
            ....|.|   |.|.::|.|||||||.|:.|.|..|:..||:||||||||||||||::|:.:|:.|
Zfish   268 LSYVESDSESDQGMRKRRAFLDMLLKTKDEDGKMLTHKDIQEEVDTFMFEGHDTTAAAMNWAIHL 332

  Fly   323 LSKNPDVQQRAFEEASELEGREK--------ESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVG 379
            |..:|:||::|.:|..|:.|..:        :.:.|||.||||:||::||||||:|.:.:|.::.
Zfish   333 LGSHPEVQRKAQQELFEVFGESERPVNTEDLKKLRYLECVIKESLRLFPSVPFFARTICDDTQIN 397

  Fly   380 KLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFL-VNEKQMHPFAFAAFSAGPRNCIGQKFAM 443
            ...||||.:|..:.|.|||||:.|||||.|.|:||| .|....||:|:..||||.||||||:||:
Zfish   398 GFKVPKGTNIVVITYALHRDPRFFPDPEEFRPERFLPENCVGRHPYAYIPFSAGLRNCIGQRFAI 462

  Fly   444 LELKTSLAMLLRSYRFLP-DKDHQPKPLAELVTKSGNGI 481
            :|.|..||.:||.:..:. .|..:.:||.|||.:...||
Zfish   463 MEEKVILAYILRYFNIVACQKREELRPLGELVLRPEQGI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	186/431 (43%)
cyp4v2a	NP_001071070.1	cytochrome_P450	68..503	CDD:477761	187/444 (42%)