Protein Alignment Cyp4s3 and cyp46a1.2

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_956755.3
• Gene: cyp46a1.2 / 393433
• ZFINID: ZDB-GENE-040426-1184
• Length: 501
• Species: Danio rerio
• Alignment Length: 529
• Identity: 140/529 - (26%)
• Similarity: 236/529 - (44%)
• Gaps: 97/529 - (18%)

  Fly     4 LALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGP-----TIG-------------ELIANVKKG 50
            |.::.::|.|.|..:|...|....|.:....:|||     .:|             .||.::
Zfish     7 LYIIFYLLSAVFTAFLAYCLYIHHLHQKYDHIPGPPRDNFLLGHSPSLTKAMYSDDSLIHDL--- 68

  Fly    51 EILNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTN 115
             .|.|    .|::|||:||.....:.::...||..|.:|.:.:......:|..|....||..|.|
Zfish    69 -FLQW----AEQYGPVYRINTLHYIAIVVHCPEATKTILMSPKYAKDPFSYSRLFNLFGKRFLGN 128

  Fly   116 G------GESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDI-YPYITLFA 173
            |      .:.|:|:|:::.|.|....|.......:|....|:.:|...||.::..: :..:....
Zfish   129 GLVTAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEMANNKTPAVMHDLVNCVT 193

  Fly   174 LDAICETAMGIKKHAQLQSDSEYVQAVQSIC-------------RVMHKQSFSFWQRLNVFFKHT 225
            ||.||:.|.|:..:...|.||.:..||: :|             |:..|.    |:.:.
Zfish   194 LDVICKVAFGVDLNFLAQKDSPFQNAVE-LCLNGMALDARDPLFRIFPKN----WKLIQ------ 247

  Fly   226 KPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGA 290
               :.|:||:         ::|...|:.||.|.......|  ||...         :|||:...|
Zfish   248 ---QIRDAAV---------LLRKTGEKWIQNRKTAVKNGE--DVPKD---------ILTQILKIA 289

  Fly   291 ELSDTDIREEVD-------TFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREKE-- 346
            |..:.:..|:::       ||...|.:||::.::||:..|.:||::.:||..|..|:.|.::|
Zfish   290 EEENVNSSEDLEQMMDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKREIS 354

  Fly   347 -----SMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDP 406
                 .:.||..|:|||||:||:.|..:|.:.||:.:..:.:|.|.|:....::..|..|.|.||
Zfish   355 NEDLGKLTYLSQVLKETLRLYPTAPGTNRWLHEDMIINGIKIPGGCSVMFSSFVSQRLEKFFKDP 419

  Fly   407 ERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF--LPDKDHQPKP 469
            .:|||:||..|..:.: :.:..|:.|||.|:||.|:.:|.|..||.||:.:.|  :|.:....|.
Zfish   420 LKFDPERFDENAPKPY-YCYYPFALGPRTCLGQVFSQMEAKVVLAKLLQRFEFSLVPGQSFDIKD 483

  Fly   470 LAELVTKSG 478
            ...|..|||
Zfish   484 TGTLRPKSG 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	124/451 (27%)
cyp46a1.2	NP_956755.3	None