DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4s3 and CYP96A10

DIOPT Version :9

Sequence 1:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001031814.1	Gene:	CYP96A10 / 3770599	AraportID:	AT4G39490	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	122/559 - (21%)
Similarity:	225/559 - (40%)	Gaps:	125/559 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TLALVAFVLWAAFL------RYLPKILNFLRLQRFAKTLPGPTIGELIANVKKGEILNWLKELRE 61
            ::|...|:|:..||      |..|....|..:      :||     |:..:.:  :.:::.|:.|
plant    10 SIAFFCFLLFRHFLINKKTHRLCPTNWPFFGM------IPG-----LLVEIHR--VYDFITEILE 61

  Fly    62 K-------HGPVFRIWFGKDLMVMFTDPEDIKQLLGNN-QLLTKSRNYELLEPWLGKGLLTNGGE 118
            .       .||.|.   ..|::|. .||.:|..::.:| ....|...::.|...||.|:.....|
plant    62 VTNLTYPCTGPCFA---NLDMLVT-VDPANIHHIMSSNFANYPKGPEFKKLFDILGDGIFNADSE 122

  Fly   119 SWHRRRK-----LLTPGFH-FRILSEFKE------PMEENCRILVRRLRTKANGESFDIYPYITL 171
            .|...||     ::.|.|. |.:.:..|:      |:.::  :...:|..... :.|..:.:.|.
plant   123 LWKDLRKSAQSMMMNPEFQKFSLATSLKKLEKGLVPLLDH--VAKEKLAVDLQ-DMFQRFTFDTT 184

  Fly   172 FAL----DAIC-ETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKP---- 227
            |.|    |..| ...|...:.|:...|:|..                      :||:|.||
plant   185 FVLATGYDPGCLSVEMPEVEFARALDDAEEA----------------------IFFRHVKPEIFW 227

  Fly   228 --------GKERE--AALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLL 282
                    |.|::  .|...|....::.|.::|:::.:..|       ..|..:|..|.....|.
plant   228 RLQGLLGLGDEKKMTKARSTLDRVCSKYIAIKRDEVSRGTN-------NVDSHSKDLLTSYMNLD 285

  Fly   283 LTQMEGGAELSDTD---IREEVDTFMFEGHDTTSSAIAFALSLLSKNPDV--------------Q 330
            .|:.:   .|:.:|   :|:.:.|||..|.|||.|.:.:...||.|||:|              :
plant   286 TTKYK---LLNPSDERFLRDTILTFMLAGRDTTGSGLTWFFWLLIKNPEVIAKIRQEINTALFQR 347

  Fly   331 QRAFEEAS------ELEGREKESMPYLEAVIKETLRIYPSVPFFSRKVLE-DLEVGKLTVPKGAS 388
            .:..::||      ....:|.:.:.||...|.|:||:||.|||..:...: |:......|...:.
plant   348 SKVDDDASNNNDSDSFSPQELKKLVYLHGAICESLRLYPPVPFQHKSPTKPDVLPSGHKVDANSK 412

  Fly   389 ISCLIYMLHRDPKNF-PDPERFDPDRFLV---NEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTS 449
            |...:|.|.|....: .|...|.|:|::.   |......:.|.:|:||||.|:|::.||:::|:.
plant   413 ILFCLYSLGRMKSVWGEDALEFKPERWISESGNSVHEPSYKFLSFNAGPRTCLGKEVAMMQMKSV 477

  Fly   450 LAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRILPR 488
            ...::::|.....:..|.:|...::....:|:::.:..|
plant   478 AVKIIQNYEMKIVEGQQIEPAPSVILHMKHGLKVTVTKR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	111/500 (22%)
CYP96A10	NP_001031814.1	CYP86A	68..509	CDD:410687	107/479 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920