Protein Alignment Cyp4s3 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_571221.2
• Gene: cyp26a1 / 30381
• ZFINID: ZDB-GENE-990415-44
• Length: 492
• Species: Danio rerio
• Alignment Length: 537
• Identity: 122/537 - (22%)
• Similarity: 205/537 - (38%)
• Gaps: 111/537 - (20%)

  Fly     1 MSTLALVAFVLWAAFLRYLPKILNFLRLQRF-----AKTLPG----PTIGE---LIANVKKGEIL 53
            :.|:.|...:..||.     |:...|.::|.     :...||    |.|||   ||...:|
Zfish    11 LCTIVLPVLLFLAAV-----KLWEMLMIRRVDPNCRSPLPPGTMGLPFIGETLQLILQRRK---- 66

  Fly    54 NWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQ-LLGNNQLLTKSRNYELLEPW-------LGK 110
             :|:..|:|:|.:::.....:..|.....::::| |||.::|::..        |       ||.
Zfish    67 -FLRMKRQKYGCIYKTHLFGNPTVRVMGADNVRQILLGEHKLVSVQ--------WPASVRTILGS 122

  Fly   111 GLLTN-GGESWHRRRKLLTPGF------HF------RILSEFKEPMEENCRILVRRLRTKANGES 162
            ..|:| .|.....::|.:...|      |:      .:.|..:|.::::..:||
Zfish   123 DTLSNVHGVQHKNKKKAIMRAFSRDALEHYIPVIQQEVKSAIQEWLQKDSCVLV----------- 176

  Fly   163 FDIYPYITLFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKP 227
               ||.:............:|.:.......:.|.|:|.:.    |.|..||.  .::|.|.....
Zfish   177 ---YPEMKKLMFRIAMRILLGFEPEQIKTDEQELVEAFEE----MIKNLFSL--PIDVPFSGLYR 232

  Fly   228 GKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAEL 292
            |..   |...:|.:....||             |...:.|:...::....|.:|:..........
Zfish   233 GLR---ARNFIHSKIEENIR-------------KKIQDDDNENEQKYKDALQLLIENSRRSDEPF 281

  Fly   293 SDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASE------------LEGREK 345
            |...::|.....:|.||:||:|.....:..|..|.:|.|:..||..|            |.....
Zfish   282 SLQAMKEAATELLFGGHETTASTATSLVMFLGLNTEVVQKVREEVQEKVEMGMYTPGKGLSMELL 346

  Fly   346 ESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFD 410
            :.:.|...||||||||.|.||...|..|:..|:....:|||.::...|...|.....||:.:.|.
Zfish   347 DQLKYTGCVIKETLRINPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADVFPNKDEFQ 411

  Fly   411 PDRFLVNEKQMHP---FAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFL-----PDKDHQP 467
            |:||:  .|.:..   |.:..|..|.|.|:|::||.:.||..|..|.:...::     |.....|
Zfish   412 PERFM--SKGLEDGSRFNYIPFGGGSRMCVGKEFAKVLLKIFLVELTQHCNWILSNGPPTMKTGP 474

  Fly   468 K--PLAELVTKSGNGIR 482
            .  |:..|.||..:.:|
Zfish   475 TVYPVDNLPTKFTSYVR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	103/462 (22%)
cyp26a1	NP_571221.2	CYP26A1	55..486	CDD:410731	109/481 (23%)