Protein Alignment Cyp4s3 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 165/492 - (33%)
• Similarity: 259/492 - (52%)
• Gaps: 30/492 - (6%)

  Fly    10 VLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGELIANVKKGEILNWLKELREKHGPVFRIWF-GK 73
            ||:.|...||.:......|::|..|......|..:.:.:..::|.|:    ||.......|. |.
  Rat    30 VLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHDLKDREFQQVLTWV----EKFPGACLQWLSGS 90

  Fly    74 DLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWL----GKGLLTNGGESWHRRRKLLTPGFHFR 134
            ...|:..||:.:|.:||.:. ...|..|:.|.||:    |.|||...|:.|.:..::|||.||:.
  Rat    91 KTRVLLYDPDYVKVVLGRSD-PKASGIYQFLAPWIVSGTGYGLLLLNGKKWFQHWRMLTPAFHYG 154

  Fly   135 ILSEFKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDS-EYV 197
            ||..:.:.|.::..|::.:. :........:|:.|::|..||.:.:.|...:...||..:| .|.
  Rat   155 ILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYT 219

  Fly   198 QAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKP 262
            :||:.:..:...:..|.:...::.:..:..|:....|.::.|:.|:.||::|:.||       :.
  Rat   220 KAVEDLNNLTFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKMRKAQL-------QN 277

  Fly   263 EAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNP 327
            |.|......||.|.|||:||..:||.|..|||.|:|.|||||||||||||:|.|::....|:.:|
  Rat   278 EEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHP 342

  Fly   328 DVQQRAFEEASELEG-------REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEV--GKLTV 383
            :.|:|..||...:.|       ...:.:.|....|||.||:||.||..||::...:..  |: ::
  Rat   343 EHQERCREEVQSILGDGTSVTWDHLDQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGR-SI 406

  Fly   384 PKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKT 448
            |||.:.:.|||.||.:|..:|:|:.|||.||..:..: |..|:..||.|.|||||::|||.|||.
  Rat   407 PKGITTTILIYGLHHNPSYWPNPKVFDPSRFSPDSPR-HSHAYLPFSGGARNCIGKQFAMNELKV 470

  Fly   449 SLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRI 485
            ::|:.|..:..|||....|.|:|.||.||.|||.||:
  Rat   471 AVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	150/434 (35%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	154/450 (34%)