Protein Alignment Cyp4s3 and Cyp4a8

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_113793.2
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 435
• Identity: 161/435 - (37%)
• Similarity: 244/435 - (56%)
• Gaps: 36/435 - (8%)

  Fly    69 IWFGKDLMVMFTDPEDIKQLLGNNQLLTKS-RNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFH 132
            :| |.::.:...||:.:|.:||.:.  .|| .:|..|.||:|.|||...|::|.:.|::|||.||
  Rat    88 LW-GSNVRIQVYDPDYMKLILGRSD--PKSHHSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFH 149

  Fly   133 FRILSEFKEPMEENCRILVRRLRTKANGES-FDIYPYITLFALDAICETAMGIKKHAQL-QSDSE 195
            :..|..:...|.::.||::.:.......:| .:|:.:|||..||.|.:.|...:...|| :....
  Rat   150 YDTLKPYVGIMADSVRIMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSQEGSVQLDRKYKS 214

  Fly   196 YVQAVQSICRVMHKQSFSFWQRLNVFFKH------TKPGKEREAALKVLHDETNRVIRLRREQLI 254
            |::||:.:      .:.||::..|:|.::      :..|::..:|.::.|:.|::||:.|:.||
  Rat   215 YIKAVEDL------NNLSFFRIRNIFHQNDIIYSLSSNGRKARSAWQLAHEHTDQVIKSRKAQL- 272

  Fly   255 QERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFA 319
                  :.|.|...|..||||.|||:||..::|.|:.|||.|:|.|||||||||||||:|.|::.
  Rat   273 ------QDEEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFMFEGHDTTASGISWI 331

  Fly   320 LSLLSKNPDVQQRAFEEASELEG-------REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLE 377
            ...|:.||:.||...:|...|.|       .:.:.|||....|||.|||||.|...||.:...:.
  Rat   332 FYALATNPEHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTPVT 396

  Fly   378 V--GKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQK 440
            .  |: ::|||.::....|.||.:|..:|:||.|||.|| ..|...|..:|..||.|.|||||::
  Rat   397 FPDGR-SLPKGITVMLSFYGLHHNPTVWPNPEVFDPYRF-APESSRHSHSFLPFSGGARNCIGKQ 459

  Fly   441 FAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRI 485
            |||.|||.::|:.|..:..|||....|.|:..||.||.|||.||:
  Rat   460 FAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKNGIYLRL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	159/431 (37%)
Cyp4a8	NP_113793.2	CYP4B-like	70..503	CDD:410771	159/432 (37%)