Protein Alignment Cyp4s3 and erg11

DIOPT Version :9

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02c
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 526
• Identity: 119/526 - (22%)
• Similarity: 207/526 - (39%)
• Gaps: 118/526 - (22%)

  Fly     5 ALVAFVLWAAFLRYLPKILNFLRLQRFAKTLP-----GPTIGELIANVKKGEILNWLKELREKHG 64
            :||:.:|..|...|:..|:|.| ..|.:|..|     .|.:|..:|......:  :.:|.|.|:|
pombe     4 SLVSILLSIALAWYVGYIINQL-TSRNSKRPPIVFHWIPFVGSAVAYGMDPYV--FFRECRAKYG 65

  Fly    65 PVFR-IWFGKDLMVMFTDPEDIKQLLGNNQL--LTKSRNY-ELLEPWLGKGLLTN-GGESWHRRR 124
            .||. :..|:. |..|...:. ...|.|.:|  |.....| .|..|..||.::.: ....:...:
pombe    66 DVFTFVCMGRK-MTAFLGVQG-NDFLFNGKLADLNAEEAYSHLTTPVFGKDVVYDIPNHVFMEHK 128

  Fly   125 KLLTPGFHFR--------ILSEFKE---------PMEENCRILVRRLRTKANGESFDIYPYITLF 172
            |.:..|..|.        ||:|...         |.:|....|::.:            |.:|::
pombe   129 KFIKSGLGFSQFRSYVPLILNEMDAFLSTSPDFGPGKEGVADLLKTM------------PVMTIY 181

  Fly   173 ALDAICETAMGIKKHAQLQS--DSEYVQAVQSICRVMHKQSFSF-WQRLNVFFKHTKPGKEREAA 234
                   ||....:.|:::.  |:.:......:.:.....:|.| |..|       ...:.|:.|
pombe   182 -------TASRTLQGAEVRKGFDAGFADLYHDLDQGFSPVNFVFPWLPL-------PRNRRRDRA 232

  Fly   235 LKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDM---LLLTQMEGGAELSDTD 296
            .|::.....::|:.||             :..::.|.       ||   |:..:...|..|.:.:
pombe   233 HKIMQKTYLKIIKDRR-------------SSTENPGT-------DMIWTLMSCKYRDGRPLKEHE 277

  Fly   297 IREEVDTFMFEGHDTTSSAIAFALSLLSKNPDV-------QQRAFEEASELEGREKESMPYLEAV 354
            |...:...:..|..|:::.|.:.|:||...|::       |:|...|..||:..:.:.||.|..|
pombe   278 IAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGENLELKFDQYKDMPLLNYV 342

  Fly   355 IKETLRIYPSVPFFSRKVLEDLEV--GKLTVP--------KGASISCLIYMLHR---DPKNFPD- 405
            |:||||::|.:....|||..||.|  .|:.:|        .|.:.:...|..|.   |||.:.|
pombe   343 IQETLRLHPPIHSHMRKVKRDLPVPGSKIVIPANNYLLAAPGLTATEEEYFTHATDFDPKRWNDR 407

  Fly   406 ------PERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF----- 459
                  .|:.|....||.:....|  :..|.||...|||::||.:.|.|.::..:..|.:
pombe   408 VNEDENAEQIDYGYGLVTKGAASP--YLPFGAGRHRCIGEQFAYMHLSTIISKFVHDYTWTLIGK 470

  Fly   460 LPDKDH 465
            :|:.|:
pombe   471 VPNVDY 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	109/496 (22%)
erg11	NP_592990.1	CypX	28..495	CDD:225035	111/501 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I1639
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050