Protein Alignment Cyp4s3 and Cyp24a1

DIOPT Version :9

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_963966.1
• Gene: Cyp24a1 / 25279
• RGDID: 2462
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 507
• Identity: 125/507 - (24%)
• Similarity: 219/507 - (43%)
• Gaps: 124/507 - (24%)

  Fly    30 RFAKTLPGPT----IGELIANVKKGEIL---NWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQ 87
            |...:|||||    :|.|:....||.:.   :.|.|..:|:|.:||:..|....|....|..::.
  Rat    53 RNVTSLPGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEA 117

  Fly    88 LLGNNQLLTKSRNYELLE--PWL--------GKGLLTNGGESWHR-----RRKLLTPGFHFR--- 134
            |     ..|:|.:.:.||  ||.        ..||:...|:.|.|     ::||:.|....:
  Rat   118 L-----YRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDK 177

  Fly   135 ----ILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDSE 195
                :|::|.|.|:|.|         ...|...|:|..:..::.::|| ..:..|:...||.::|
  Rat   178 KINEVLADFLERMDELC---------DERGRIPDLYSELNKWSFESIC-LVLYEKRFGLLQKETE 232

  Fly   196 -----YVQAVQSICRV----------MHKQ-SFSFWQ----RLNVFFKHTKPGKEREAALKVLHD 240
                 ::.|::::...          :||: :...||    ..:..||..||..:
  Rat   233 EEALTFITAIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCID---------- 287

  Fly   241 ETNRVIRLRREQLIQERNEWKPEA-------EQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIR 298
              ||:          :|...:|.|       :||.:..|...|.:..|.|..:|
  Rat   288 --NRL----------QRYSQQPGADFLCDIYQQDHLSKKELYAAVTELQLAAVE----------- 329

  Fly   299 EEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASEL-------EGREKESMPYLEAVIK 356
                        ||::::.:.|..||:||..|:|..:|...:       ...:..:||||:|.:|
  Rat   330 ------------TTANSLMWILYNLSRNPQAQRRLLQEVQSVLPDNQTPRAEDLRNMPYLKACLK 382

  Fly   357 ETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEKQM 421
            |::|:.|||||.:|.:.:...:|:..:|||..::....:|.....||.|..:|.|:|:|..||::
  Rat   383 ESMRLTPSVPFTTRTLDKPTVLGEYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKKI 447

  Fly   422 HPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAEL 473
            :|||...|..|.|.|||::.|.|:|..:|..:::.|..:. .|::|..:..|
  Rat   448 NPFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKYDIVA-TDNEPVEMLHL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	123/496 (25%)
Cyp24a1	NP_963966.1	CYP24A1	90..508	CDD:410738	113/470 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910