Protein Alignment Cyp4s3 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_663708.1
• Gene: Cyp4x1 / 246767
• RGDID: 628719
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 505
• Identity: 165/505 - (32%)
• Similarity: 261/505 - (51%)
• Gaps: 36/505 - (7%)

  Fly     4 LALV---AFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGELIANVK--KGEILNWLKELREKH 63
            ||||   |.||..|...||.:    .||.|..:..||||...|:.:.|  :.:.:..|.|:.:::
  Rat    16 LALVFCLALVLMQAVKLYLRR----QRLLRDLRPFPGPTAHWLLGHQKFLQEDNMEKLDEIVKEY 76

  Fly    64 GPVFRIWFGK-DLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLL 127
            ...|..|.|. .......||:..|..|......|:.. ::|:.|:||:|||...|..|.:.|.||
  Rat    77 PCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKTQYL-HQLMTPFLGRGLLNLDGPRWFQHRCLL 140

  Fly   128 TPGFHFRILSEFKEPMEENCRILVRRL-RTKANGE-SFDIYPYITLFALDAICETAMGIKKHAQL 190
            ||.||..||....:.|..:..:::.:. :|....| :.:::.:|.|..||.|.:.|.|.:.:.|:
  Rat   141 TPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQI 205

  Fly   191 QSDSE-YVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLI 254
            ....| ||:|...:..::..:.::||...::.||.:..|...:...||:|..|.::|:.|::.|
  Rat   206 NGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTEKIIQDRKKTL- 269

  Fly   255 QERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFA 319
                  |.:..|||....:.  |||::|..|.......||.|:|.||:|||:.|||.::::|::.
  Rat   270 ------KDQVNQDDTQTSQN--FLDIVLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWL 326

  Fly   320 LSLLSKNPDVQQRAFEE-------ASELEGREKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLE 377
            |..|:.||:.|.|...|       .|.:...:.:.:||....||||||:.|.:|..||::.:.|.
  Rat   327 LYCLALNPEHQDRCRTEIRSILGDGSSITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLT 391

  Fly   378 V--GKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFL-VNEKQMHPFAFAAFSAGPRNCIGQ 439
            :  |. ::|.|.::...|:.||.:|..:.||:.|||.||. .|.:|.||.||..||:||||||||
  Rat   392 LPDGH-SLPAGMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQ 455

  Fly   440 KFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRI--LP 487
            :|||||||.::|:.|..:|...|....|...:..|.:..:||.|.:  ||
  Rat   456 QFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLRPKHGIYLHLKKLP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	141/432 (33%)
Cyp4x1	NP_663708.1	CYP4B-like	66..500	CDD:410771	143/444 (32%)