Protein Alignment Cyp4s3 and Cyp4a2

DIOPT Version :10

• Sequence 1: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 488
• Identity: 165/488 - (33%)
• Similarity: 259/488 - (53%)
• Gaps: 29/488 - (5%)

  Fly    10 VLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGELIANVKKGEILNWLKELREKHGPVFRIWF-GK 73
            ||:.|...||.:......|::|..|......|..:.:.:..::|.|:    ||.......|. |.
  Rat    30 VLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWV----EKFPGACLQWLSGS 90

  Fly    74 DLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPGFHFRILSE 138
            ...|:..||:.:|.:||.:.    .:.|:.|.||:|.|||...|:.|.:.|::|||.||:.||..
  Rat    91 TARVLLYDPDYVKVVLGRSD----PKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKP 151

  Fly   139 FKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDAICETAMGIKKHAQLQSDS-EYVQAVQ 201
            :.:.|.::..|::.:. :........:|:.|::|..||.:.:.|...:...||..:| .|.:||:
  Rat   152 YVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVE 216

  Fly   202 SICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQ 266
            .:..::..:..|.:...::.:..:..|:....|.::.|:.|:.||:.|:.||       :.|.|.
  Rat   217 DLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQL-------QNEEEL 274

  Fly   267 DDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQ 331
            .....||.|.|||:||..:||.|..|||.|:|.|||||||||||||:|.|::....|:.:|:.|:
  Rat   275 QKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQE 339

  Fly   332 RAFEEASELEG-------REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEV--GKLTVPKGA 387
            |..||...:.|       ...:.|||....|||.||:|..||..||::...:..  |: ::|||.
  Rat   340 RCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGR-SIPKGI 403

  Fly   388 SISCLIYMLHRDPKNFPDPERFDPDRFLVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAM 452
            .::.|||.||.:|..:|:|:.|||.||..:..: |..|:..||.|.|||||::|||.|||.::|:
  Rat   404 RVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPR-HSHAYLPFSGGARNCIGKQFAMNELKVAVAL 467

  Fly   453 LLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRI 485
            .|..:..|||....|.|:..||.||.|||.||:
  Rat   468 TLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	150/430 (35%)
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	154/446 (35%)